※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Sus-2980	ENSSSCG00000011349.4	P51525
2		LLPS-Sus-3896	ENSSSCG00000016626.3	A0A286ZZ96	CFTR
3		LLPS-Sus-1609	ENSSSCG00000038003.1	A0A286ZPK2	ITK
4		LLPS-Sus-2661	ENSSSCG00000028662.2	I3L6S5	PDE3A
5		LLPS-Sus-0672	ENSSSCG00000023915.2	I3LED1	SLC2A4
6		LLPS-Sus-4565	ENSSSCG00000026985.2	A0A286ZJ92	SNAP25
7		LLPS-Sus-2046	ENSSSCG00000009589.4	A0A286ZZ61	SYK