Corchorus capsularis      Nuclear speckle


※ Nuclear speckle introduction

    Nuclear speckles or splicing speckles, also known as interchromatin granule clusters, are membrane-less nuclear organelles enriched in pre-mRNA splicing and transcription factors and play important roles in RNA metabolism, such as transcription, pre-mRNA splicing, 3′-end mRNA processing, and execution of mRNA nuclear export (1; 2). They are dynamic subnuclear structures, and their size, shape, and number can vary accompanied with RNA regulation, nuclear speckles disperse in high activity of mRNA processing when transcription or pre-mRNA splicing is inhibited, GSK-3β can regulate assembly of nuclear speckles (2). Because many naturally intronless mRNAs, including eight exogenously expressed and four endogenous ones, are proved to be associate with NSs, So Nuclear speckles (NSs) are thought to serve as splicing factor storage sites (3).

Reference
1. Lee, K. H., Zhang, P., Kim, H. J., Mitrea, D. M., Sarkar, M., Freibaum, B. D., et al. (2016) C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. Cell, 167(3), 774-788 e717. PMID: 27768896
2. Wang, K., Wang, L., Wang, J., Chen, S., Shi, M., & Cheng, H. (2018) Intronless mRNAs transit through nuclear speckles to gain export competence. J Cell Biol, 217(11), 3912-3929. PMID: 30194269
3. An, Y., Zou, Y., Cao, Y., Yao, M., Ma, N., Wu, Y., et al. (2019) The nuclear GSK-3beta regulated post-transcriptional processing of mRNA through phosphorylation of SC35. Mol Cell Biochem, 451(1-2), 55-67. PMID: 30030778


There are 56 genes.  Reviewed (0 or Unreviewed (56

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Coc-1562
CCACVL1_03750
A0A1R3JXW4
CCACVL1_03750
2
LLPS-Coc-0121
CCACVL1_04232
A0A1R3JUK4
CCACVL1_04232
3
LLPS-Coc-0107
CCACVL1_04714
A0A1R3JQH3
CCACVL1_04714
4
LLPS-Coc-0152
CCACVL1_06746
A0A1R3JDD2
CCACVL1_06746
5
LLPS-Coc-1581
CCACVL1_07697
A0A1R3J4E0
CCACVL1_07697
6
LLPS-Coc-1735
CCACVL1_08030
A0A1R3J2K6
CCACVL1_08030
7
LLPS-Coc-1165
CCACVL1_08414
A0A1R3J0N9
CCACVL1_08414
8
LLPS-Coc-0154
CCACVL1_09272
A0A1R3IWZ1
CCACVL1_09272
9
LLPS-Coc-0713
CCACVL1_09331
A0A1R3IWP0
CCACVL1_09331
10
LLPS-Coc-1084
CCACVL1_09491
A0A1R3IVX0
CCACVL1_09491
11
LLPS-Coc-0165
CCACVL1_09553
A0A1R3IVF6
CCACVL1_09553
12
LLPS-Coc-1613
CCACVL1_10560
A0A1R3IQQ5
CCACVL1_10560
13
LLPS-Coc-1831
CCACVL1_10593
A0A1R3IQN7
CCACVL1_10593
14
LLPS-Coc-1029
CCACVL1_10894
A0A1R3IP78
CCACVL1_10894
15
LLPS-Coc-1932
CCACVL1_11472
A0A1R3IL00
CCACVL1_11472
16
LLPS-Coc-1783
CCACVL1_11656
A0A1R3IK60
CCACVL1_11656
17
LLPS-Coc-1205
CCACVL1_12181
A0A1R3IGV2
CCACVL1_12181
18
LLPS-Coc-1901
CCACVL1_13210
A0A1R3IBU5
CCACVL1_13210
19
LLPS-Coc-1203
CCACVL1_13280
A0A1R3IBH5
CCACVL1_13280
20
LLPS-Coc-1594
CCACVL1_13682
A0A1R3IA99
CCACVL1_13682
21
LLPS-Coc-0108
CCACVL1_14360
A0A1R3I7E7
CCACVL1_14360
22
LLPS-Coc-2136
CCACVL1_14430
A0A1R3I769
CCACVL1_14430
23
LLPS-Coc-0668
CCACVL1_14453
A0A1R3I6Z8
CCACVL1_14453
24
LLPS-Coc-0879
CCACVL1_14596
A0A1R3I6G7
CCACVL1_14596
25
LLPS-Coc-1192
CCACVL1_15331
A0A1R3I2R4
CCACVL1_15331
26
LLPS-Coc-0724
CCACVL1_15533
A0A1R3I208
CCACVL1_15533
27
LLPS-Coc-0544
CCACVL1_16134
A0A1R3HYX9
CCACVL1_16134
28
LLPS-Coc-0095
CCACVL1_16615
A0A1R3HWA4
CCACVL1_16615
29
LLPS-Coc-0764
CCACVL1_17958
A0A1R3HNX5
CCACVL1_17960
30
LLPS-Coc-1833
CCACVL1_18414
A0A1R3HLI1
CCACVL1_18414
31
LLPS-Coc-1269
CCACVL1_21260
A0A1R3H7M9
CCACVL1_21260
32
LLPS-Coc-1625
CCACVL1_21517
A0A1R3H576
CCACVL1_21517
33
LLPS-Coc-1486
CCACVL1_22000
A0A1R3H1D4
CCACVL1_22000
34
LLPS-Coc-0825
CCACVL1_22073
A0A1R3H120
CCACVL1_22073
35
LLPS-Coc-1404
CCACVL1_22221
A0A1R3H0I6
CCACVL1_22221
36
LLPS-Coc-0415
CCACVL1_23088
A0A1R3GV70
CCACVL1_23088
37
LLPS-Coc-1161
CCACVL1_23202
A0A1R3GV39
CCACVL1_23202
38
LLPS-Coc-1353
CCACVL1_23425
A0A1R3GTY9
CCACVL1_23425
39
LLPS-Coc-1346
CCACVL1_23559
A0A1R3GTL6
CCACVL1_23559
40
LLPS-Coc-2308
CCACVL1_25172
A0A1R3GLL9
CCACVL1_25172
41
LLPS-Coc-1183
CCACVL1_25174
A0A1R3GLQ7
CCACVL1_25174
42
LLPS-Coc-1327
CCACVL1_25522
A0A1R3GJN5
CCACVL1_25522
43
LLPS-Coc-0949
CCACVL1_25820
A0A1R3GGZ0
CCACVL1_25820
44
LLPS-Coc-0648
CCACVL1_26194
A0A1R3GFL6
CCACVL1_26194
45
LLPS-Coc-0930
CCACVL1_26403
A0A1R3GEX5
CCACVL1_26403
46
LLPS-Coc-2256
CCACVL1_26916
A0A1R3GCU2
CCACVL1_26916
47
LLPS-Coc-0022
CCACVL1_27297
A0A1R3GBA1
CCACVL1_27297
48
LLPS-Coc-0687
CCACVL1_28376
A0A1R3G6S5
CCACVL1_28376
49
LLPS-Coc-1308
CCACVL1_28463
A0A1R3G6E8
CCACVL1_28463
50
LLPS-Coc-0501
CCACVL1_28485
A0A1R3G6C6
CCACVL1_28485
51
LLPS-Coc-0281
CCACVL1_28696
A0A1R3G5J9
CCACVL1_28696
52
LLPS-Coc-2266
CCACVL1_29543
A0A1R3G1D1
CCACVL1_29543
53
LLPS-Coc-0907
CCACVL1_30188
A0A1R3FYF2
CCACVL1_30188
54
LLPS-Coc-1703
CCACVL1_30456
A0A1R3FXE9
CCACVL1_30456
55
LLPS-Coc-0227
CCACVL1_30682
A0A1R3FW12
CCACVL1_30682
56
LLPS-Coc-1890
CCACVL1_30900
A0A1R3FV53
CCACVL1_30900