Bos taurus      Neuronal granule


※ Neuronal granule introduction

    Neuronal granules are also referred to as neuronal transport granules, RNA-transporting granules, neuronal RNA granules, dendritic P-body like structures (dlP-bodies), FMRP granules and Staufen granules(1,2). They are broadly identified by the presence of two highly conserved proteins: Staufen, a double-stranded RNA-binding protein and FMRP. As a kind of cytoplasmic RNP bodies located in Cytoplasm of neurons, neuronal transport RNPs have highly specialized functions and have been shown to interact or co-localize with components of GW/P bodies (1), it's microtubule-dependent and contain Silenced mRNAs and ribosomes components. Neuronal RNA bodies is of spherical shape with fluid characteristics, proved to be associated with rotein synthesis in response to exogenous stimuli (2).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973
2. Hirano, M., Muto, M., Sakai, M., Kondo, H., Kobayashi, S., Kariwa, H., Yoshii, K.(2017) Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease. Proc Natl Acad Sci U S A, 114, 9960–9965. PMID: 28847946
3. Darling, A. L., Liu, Y., Oldfield, C. J., & Uversky, V. N. (2018) Intrinsically Disordered Proteome of Human Membrane-Less Organelles. Proteomics, 18(5-6), e1700193. PMID: 27838525


There are 44 genes.  Reviewed (10 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-0040
ENSBTAG00000035907.4
G5E631
DDX3X
2
LLPS-Bot-0144
ENSBTAG00000018423.6
F1MBQ8
DDX5
3
LLPS-Bot-0075
ENSBTAG00000014534.6
P68103
EEF1A1
4
LLPS-Bot-0108
ENSBTAG00000016311.5
P68102
EIF2S1
5
LLPS-Bot-0047
ENSBTAG00000005969.3
A0A140T862
EIF2S2
6
LLPS-Bot-0229
ENSBTAG00000016174.5
E1B8K6
NCL
7
LLPS-Bot-0244
ENSBTAG00000012152.5
G3N361
NONO
8
LLPS-Bot-0175
ENSBTAG00000003934.6
Q1LZD9
PSPC1
9
LLPS-Bot-0094
ENSBTAG00000003228.4
P39872
RPL3
10
LLPS-Bot-0222
ENSBTAG00000016328.6
E1BQ37
SFPQ
11
LLPS-Bot-0751
ENSBTAG00000002076.6
12
LLPS-Bot-2364
ENSBTAG00000007606.6
13
LLPS-Bot-1908
ENSBTAG00000008498.3
Q3T0I4
ALYREF
14
LLPS-Bot-1651
ENSBTAG00000016744.6
Q1LZB6
CAPRIN1
15
LLPS-Bot-2616
ENSBTAG00000007480.6
Q3SZN4
CIRBP
16
LLPS-Bot-4712
ENSBTAG00000009995.6
E1BGL4
CPEB4
17
LLPS-Bot-0477
ENSBTAG00000009906.6
Q0IIK5
DDX1
18
LLPS-Bot-0575
ENSBTAG00000009106.5
F1MBF0
EIF2A
19
LLPS-Bot-3612
ENSBTAG00000009522.6
Q9N0T5
EIF4E
20
LLPS-Bot-3427
ENSBTAG00000021046.6
A2VDK5
ELAVL4
21
LLPS-Bot-0548
ENSBTAG00000017755.6
A8E651
EWSR1
22
LLPS-Bot-2040
ENSBTAG00000012552.6
F1MXQ7
FMR1
23
LLPS-Bot-3002
ENSBTAG00000016457.6
F1N4M9
FXR1
24
LLPS-Bot-3091
ENSBTAG00000005462.6
E1B9L5
FXR2
25
LLPS-Bot-1371
ENSBTAG00000020309.6
Q32LC7
G3BP1
26
LLPS-Bot-0592
ENSBTAG00000016929.5
F6RSR1
HNRNPA0
27
LLPS-Bot-4070
ENSBTAG00000001553.6
P09867
HNRNPA1
28
LLPS-Bot-0622
ENSBTAG00000005726.6
Q2HJ60
HNRNPA2B1
29
LLPS-Bot-1372
ENSBTAG00000013627.6
Q3ZC44
HNRNPAB
30
LLPS-Bot-0281
ENSBTAG00000013952.6
A6H6Y0
HNRNPD
31
LLPS-Bot-3098
ENSBTAG00000012497.4
Q29RQ2
KHDRBS1
32
LLPS-Bot-a067
ENSBTAG00000003580.6
F1MUS9
PSD
33
LLPS-Bot-1237
ENSBTAG00000008881.6
E1BMW9
PURA
34
LLPS-Bot-1333
ENSBTAG00000025848.4
F6RBQ9
RBM3
35
LLPS-Bot-1039
ENSBTAG00000033727.4
F1MAV3
RBPMS
36
LLPS-Bot-3583
ENSBTAG00000021251.5
A6QLV0
RIPK4
37
LLPS-Bot-1461
ENSBTAG00000011070.6
Q5E9T9
RTCB
38
LLPS-Bot-1060
ENSBTAG00000021944.3
Q3T0S7
RTRAF
39
LLPS-Bot-1635
ENSBTAG00000008072.6
Q3ZBU5
SRSF10
40
LLPS-Bot-1490
ENSBTAG00000000241.6
F1MH34
STAU1
41
LLPS-Bot-0701
ENSBTAG00000006672.6
F1MCT8
SYNCRIP
42
LLPS-Bot-0585
ENSBTAG00000008816.6
A4IF63
TRIM2
43
LLPS-Bot-3083
ENSBTAG00000003565.5
A7MB36
TRIM3
44
LLPS-Bot-4552
ENSBTAG00000015604.5
Q08DL3
ZNF385A