Rattus norvegicus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 41 genes.  Reviewed (1 or Unreviewed (40

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ran-0019
ENSRNOG00000012693.5
Q03346
Pmpcb
2
LLPS-Ran-3874
ENSRNOG00000025808.5
D3ZX08
Aars2
3
LLPS-Ran-1470
ENSRNOG00000002813.6
Q3KRD0
Dars2
4
LLPS-Ran-2790
ENSRNOG00000019817.3
D4A7Q5
Ddx28
5
LLPS-Ran-1336
ENSRNOG00000029194.5
Q5BJS0
Dhx30
6
LLPS-Ran-4511
ENSRNOG00000010673.7
Q5EBA0
Eral1
7
LLPS-Ran-2358
ENSRNOG00000011667.6
Q5XIG7
Fastk
8
LLPS-Ran-2342
ENSRNOG00000024335.5
D3ZFR0
Fastkd1
9
LLPS-Ran-2596
ENSRNOG00000023923.6
Q5M7V7
Fastkd2
10
LLPS-Ran-3159
ENSRNOG00000003392.7
F1LRK4
Grsf1
11
LLPS-Ran-2980
ENSRNOG00000003049.7
O70351
Hsd17b10
12
LLPS-Ran-3526
ENSRNOG00000045920.2
M0RDI5
Mcu
13
LLPS-Ran-3051
ENSRNOG00000015582.6
A0A0G2K502
Me2
14
LLPS-Ran-1888
ENSRNOG00000027901.3
D3ZK81
Mrm1
15
LLPS-Ran-2631
ENSRNOG00000043267.1
D3ZGI8
Mrm2
16
LLPS-Ran-4754
ENSRNOG00000037238.3
D3ZQG0
Mrm3
17
LLPS-Ran-3241
ENSRNOG00000006968.5
D4A4A9
Mrpl19
18
LLPS-Ran-0922
ENSRNOG00000014890.5
D3ZXF8
Mrpl43
19
LLPS-Ran-0462
ENSRNOG00000011639.6
Q3B8R7
Mrpl47
20
LLPS-Ran-2825
ENSRNOG00000007043.4
B5DF07
Mrpp3
21
LLPS-Ran-2018
ENSRNOG00000017272.7
D4A3E8
Mrps27
22
LLPS-Ran-4199
ENSRNOG00000011839.5
B0BN56
Mrps31
23
LLPS-Ran-1854
ENSRNOG00000003797.6
Q5I0K8
Mrps7
24
LLPS-Ran-0664
ENSRNOG00000016201.5
B0BN68
Mrps9
25
LLPS-Ran-0877
ENSRNOG00000004492.6
Q6P6Q6
Mterf3
26
LLPS-Ran-4007
ENSRNOG00000016578.6
D3ZPN5
Mtpap
27
LLPS-Ran-3433
ENSRNOG00000052386.1
Q5FVQ8
Nlrx1
28
LLPS-Ran-2751
ENSRNOG00000002055.6
A0A0G2K602
Noa1
29
LLPS-Ran-0983
ENSRNOG00000003600.6
G3V6G7
Pnpt1
30
LLPS-Ran-0843
ENSRNOG00000024879.5
D3ZYB6
Polrmt
31
LLPS-Ran-1809
ENSRNOG00000000987.8
A2VD13
Ptcd1
32
LLPS-Ran-3893
ENSRNOG00000028403.5
D4A9I4
Ptcd2
33
LLPS-Ran-3181
ENSRNOG00000009084.6
D4A6T2
Rpusd3
34
LLPS-Ran-3434
ENSRNOG00000011567.6
Q4QQT0
Rpusd4
35
LLPS-Ran-1334
ENSRNOG00000005686.6
F1LPV8
Suclg2
36
LLPS-Ran-2613
ENSRNOG00000000392.6
Q5EBA1
Supv3l1
37
LLPS-Ran-0519
ENSRNOG00000056223.1
Q811P6
Tfb1m
38
LLPS-Ran-3444
ENSRNOG00000039567.3
Q5U2R4
Trmt10c
39
LLPS-Ran-2329
ENSRNOG00000043189.3
Q5XFW2
Trub2
40
LLPS-Ran-3514
ENSRNOG00000014935.6
D3ZA68
Twnk
41
LLPS-Ran-2666
ENSRNOG00000017100.6
Q925S8
Yme1l1