Nomascus leucogenys      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 40 genes.  Reviewed (0 or Unreviewed (40

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nol-1117
ENSNLEG00000035341.1
A0A2I3FPQ0
2
LLPS-Nol-1605
ENSNLEG00000026583.2
M3ZAV0
AARS2
3
LLPS-Nol-0549
ENSNLEG00000015309.2
G1RZB2
DARS2
4
LLPS-Nol-0790
ENSNLEG00000006367.3
A0A2I3GH65
DHX30
5
LLPS-Nol-0403
ENSNLEG00000002994.3
G1QS33
ERAL1
6
LLPS-Nol-3005
ENSNLEG00000004192.2
G1QW03
FASTK
7
LLPS-Nol-0905
ENSNLEG00000004866.2
G1QYB0
FASTKD1
8
LLPS-Nol-4317
ENSNLEG00000007116.3
G1R654
FASTKD2
9
LLPS-Nol-3501
ENSNLEG00000007580.2
A0A2I3FPH0
FASTKD5
10
LLPS-Nol-0819
ENSNLEG00000015997.2
G1S1N0
HSD17B10
11
LLPS-Nol-2622
ENSNLEG00000003691.3
M3ZAS6
KIAA0391
12
LLPS-Nol-4060
ENSNLEG00000004596.2
A0A2I3G6S7
LOC100580287
13
LLPS-Nol-4581
ENSNLEG00000011060.2
G1RJM7
LOC100584673
14
LLPS-Nol-3902
ENSNLEG00000016456.3
G1S385
MCU
15
LLPS-Nol-1124
ENSNLEG00000011833.3
A0A2I3HV70
ME2
16
LLPS-Nol-3155
ENSNLEG00000002300.1
G1QPE0
MRM1
17
LLPS-Nol-2570
ENSNLEG00000034773.1
A0A2I3FYA6
MRM2
18
LLPS-Nol-0759
ENSNLEG00000033176.1
A0A2I3G0F4
MRM3
19
LLPS-Nol-3109
ENSNLEG00000001142.2
G1QKB4
MRPL19
20
LLPS-Nol-2976
ENSNLEG00000014812.2
A0A2I3FU32
MRPL43
21
LLPS-Nol-3228
ENSNLEG00000005831.2
G1R1J4
MRPL47
22
LLPS-Nol-1182
ENSNLEG00000032219.1
A0A2I3GVF9
MRPS27
23
LLPS-Nol-3777
ENSNLEG00000001164.3
G1QKE1
MRPS31
24
LLPS-Nol-3575
ENSNLEG00000032880.1
A0A2I3FZS6
MRPS9
25
LLPS-Nol-4624
ENSNLEG00000003582.3
G1QTT7
MTERF3
26
LLPS-Nol-4647
ENSNLEG00000017059.3
G1S5C9
MTPAP
27
LLPS-Nol-0800
ENSNLEG00000007389.3
A0A2I3HHD2
NLRX1
28
LLPS-Nol-0743
ENSNLEG00000008853.3
G1RC61
NOA1
29
LLPS-Nol-0142
ENSNLEG00000009342.2
G1RDW6
PMPCB
30
LLPS-Nol-4506
ENSNLEG00000009354.3
G1RDY0
PNPT1
31
LLPS-Nol-2338
ENSNLEG00000000718.3
G1QJ40
POLRMT
32
LLPS-Nol-2946
ENSNLEG00000004516.2
G1QX45
PTCD2
33
LLPS-Nol-2515
ENSNLEG00000004214.3
G1QVX8
RPUSD3
34
LLPS-Nol-2109
ENSNLEG00000007465.2
G1R7B3
RPUSD4
35
LLPS-Nol-4033
ENSNLEG00000007553.3
A0A2I3GR90
SUCLG2
36
LLPS-Nol-4264
ENSNLEG00000011521.3
G1RLC7
SUPV3L1
37
LLPS-Nol-3292
ENSNLEG00000034352.1
A0A2I3HKK2
TFB1M
38
LLPS-Nol-2069
ENSNLEG00000017556.3
G1S716
TRUB2
39
LLPS-Nol-3069
ENSNLEG00000014818.3
G1RXP1
TWNK
40
LLPS-Nol-4065
ENSNLEG00000016905.3
A0A2I3HGS4
YME1L1