Nicotiana attenuata      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nia-0451
A4A49_00532
A0A314L8F6
A4A49_00532
2
LLPS-Nia-2448
A4A49_05069
A0A314KWX3
A4A49_05069
3
LLPS-Nia-2604
A4A49_08178
A0A314KXA2
A4A49_08178
4
LLPS-Nia-1829
A4A49_09774
A0A1J6ILF5
A4A49_09774
5
LLPS-Nia-0150
A4A49_11819
A0A314L0Z1
A4A49_11819
6
LLPS-Nia-1847
A4A49_31275
A0A1J6J4Y8
A4A49_31275
7
LLPS-Nia-0083
A4A49_31479
A0A314KQA8
A4A49_31479
8
LLPS-Nia-2122
A4A49_34224
A0A1J6KI38
A4A49_34224
9
LLPS-Nia-0126
A4A49_36975
A0A314KT71
A4A49_36975
10
LLPS-Nia-0498
A4A49_11498
A0A314KWN5
BPG2_0
11
LLPS-Nia-0031
A4A49_21644
A0A314LFR0
ERG
12
LLPS-Nia-2454
A4A49_06091
A0A1J6IWW2
FTSH4_1
13
LLPS-Nia-1340
A4A49_03258
A0A314L3B2
MTERF9
14
LLPS-Nia-0408
A4A49_19542
A0A314KV62
PNP2
15
LLPS-Nia-1310
A4A49_26026
A0A314L6B3
PRORP1_1
16
LLPS-Nia-1481
A4A49_05047
A0A1J6IVI7
PRPS9_0
17
LLPS-Nia-0179
A4A49_24988
A0A1J6K8X7
RPOT2-TOM