Mus musculus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 42 genes.  Reviewed (2 or Unreviewed (40

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mum-1373
ENSMUSG00000032480.17
Q99PU8
Dhx30
2
LLPS-Mum-3787
ENSMUSG00000009647.13
Q3UMR5
Mcu
3
LLPS-Mum-4122
ENSMUSG00000023938.8
Q14CH7
Aars2
4
LLPS-Mum-3290
ENSMUSG00000026709.10
Q8BIP0
Dars2
5
LLPS-Mum-4296
ENSMUSG00000045538.6
Q9CWT6
Ddx28
6
LLPS-Mum-4232
ENSMUSG00000020832.14
Q9CZU4
Eral1
7
LLPS-Mum-3739
ENSMUSG00000028959.14
Q9JIX9
Fastk
8
LLPS-Mum-3859
ENSMUSG00000027086.16
Q6DI86
Fastkd1
9
LLPS-Mum-4217
ENSMUSG00000025962.15
Q922E6
Fastkd2
10
LLPS-Mum-3615
ENSMUSG00000079043.2
Q7TMV3
Fastkd5
11
LLPS-Mum-3766
ENSMUSG00000044221.14
Q8C5Q4
Grsf1
12
LLPS-Mum-4721
ENSMUSG00000025260.10
O08756
Hsd17b10
13
LLPS-Mum-3716
ENSMUSG00000021023.14
Q8JZY4
Kiaa0391
14
LLPS-Mum-4744
ENSMUSG00000024556.3
Q99KE1
Me2
15
LLPS-Mum-3524
ENSMUSG00000018405.7
Q99J25
Mrm1
16
LLPS-Mum-2410
ENSMUSG00000029557.7
Q9CPY0
Mrm2
17
LLPS-Mum-3357
ENSMUSG00000038046.4
Q5ND52
Mrm3
18
LLPS-Mum-4634
ENSMUSG00000030045.10
Q9D338
Mrpl19
19
LLPS-Mum-4686
ENSMUSG00000025208.8
Q99N89
Mrpl43
20
LLPS-Mum-3597
ENSMUSG00000037531.8
Q8K2Y7
Mrpl47
21
LLPS-Mum-3772
ENSMUSG00000041632.7
Q8BK72
Mrps27
22
LLPS-Mum-1331
ENSMUSG00000031533.4
Q61733
Mrps31
23
LLPS-Mum-3305
ENSMUSG00000046756.10
Q80X85
Mrps7
24
LLPS-Mum-4355
ENSMUSG00000060679.14
Q9D7N3
Mrps9
25
LLPS-Mum-4472
ENSMUSG00000021519.11
Q8R3J4
Mterf3
26
LLPS-Mum-4434
ENSMUSG00000024234.7
Q9D0D3
Mtpap
27
LLPS-Mum-4568
ENSMUSG00000032109.15
Q3TL44
Nlrx1
28
LLPS-Mum-4651
ENSMUSG00000036285.10
Q9JJG9
Noa1
29
LLPS-Mum-3938
ENSMUSG00000029017.13
Q9CXT8
Pmpcb
30
LLPS-Mum-3441
ENSMUSG00000020464.15
Q8K1R3
Pnpt1
31
LLPS-Mum-1229
ENSMUSG00000020329.12
Q8BKF1
Polrmt
32
LLPS-Mum-3343
ENSMUSG00000029624.10
Q8C2E4
Ptcd1
33
LLPS-Mum-3725
ENSMUSG00000021650.7
Q8R3K3
Ptcd2
34
LLPS-Mum-3120
ENSMUSG00000051169.14
Q14AI6
Rpusd3
35
LLPS-Mum-3790
ENSMUSG00000032044.4
Q9CWX4
Rpusd4
36
LLPS-Mum-3368
ENSMUSG00000061838.7
Q9Z2I8
Suclg2
37
LLPS-Mum-4135
ENSMUSG00000020079.15
Q80YD1
Supv3l1
38
LLPS-Mum-4950
ENSMUSG00000036983.7
Q8JZM0
Tfb1m
39
LLPS-Mum-3916
ENSMUSG00000044763.8
Q3UFY8
Trmt10c
40
LLPS-Mum-4015
ENSMUSG00000039826.13
Q91WG3
Trub2
41
LLPS-Mum-3606
ENSMUSG00000025209.4
Q8CIW5
Twnk
42
LLPS-Mum-3470
ENSMUSG00000026775.9
O88967
Yme1l1