Gaeumannomyces graminis      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gag-0587
GGTG_00785
J3NHP8
20341243
2
LLPS-Gag-0938
GGTG_00957
J3NI74
20341415
3
LLPS-Gag-1356
GGTG_03078
J3NP72
20343536
4
LLPS-Gag-0868
GGTG_04386
J3NSY7
20344844
5
LLPS-Gag-0550
GGTG_06159
J3NY04
20346617
6
LLPS-Gag-1557
GGTG_08088
J3P3K2
20348546
7
LLPS-Gag-0602
GGTG_08403
J3P4G6
20348861
8
LLPS-Gag-0050
GGTG_09131
J3P6J0
20349589