Ciona savignyi      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 15 genes.  Reviewed (0 or Unreviewed (15

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cis-0139
ENSCSAVG00000002095.1
H2YDW9
2
LLPS-Cis-0334
ENSCSAVG00000006502.1
H2Z0K8
3
LLPS-Cis-0363
ENSCSAVG00000004721.1
H2YRF1
4
LLPS-Cis-0594
ENSCSAVG00000000002.1
H2Y3V4
5
LLPS-Cis-0610
ENSCSAVG00000000440.1
H2Y632
6
LLPS-Cis-0876
ENSCSAVG00000002478.1
H2YFV4
7
LLPS-Cis-0891
ENSCSAVG00000006341.1
H2YZQ0
8
LLPS-Cis-1077
ENSCSAVG00000002352.1
H2YF62
9
LLPS-Cis-1096
ENSCSAVG00000003646.1
H2YLA3
10
LLPS-Cis-1247
ENSCSAVG00000009623.1
H2ZFI3
11
LLPS-Cis-1403
ENSCSAVG00000004151.1
H2YNN1
12
LLPS-Cis-1627
ENSCSAVG00000003930.1
H2YML1
13
LLPS-Cis-1745
ENSCSAVG00000011299.1
H2ZNS2
14
LLPS-Cis-1802
ENSCSAVG00000006478.1
H2Z0G1
15
LLPS-Cis-1984
ENSCSAVG00000006163.1
H2YYQ6