Ciona intestinalis      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cii-0475
ENSCING00000024450.1
F6WR46
2
LLPS-Cii-1165
ENSCING00000007717.3
F6ZJ82
3
LLPS-Cii-1334
ENSCING00000020685.1
H2XL44
4
LLPS-Cii-1600
ENSCING00000008091.3
F6Z672
5
LLPS-Cii-1636
ENSCING00000015328.2
F7APG8
6
LLPS-Cii-1690
ENSCING00000003676.3
F6ZV18
7
LLPS-Cii-1712
ENSCING00000019042.1
H2XVY6
8
LLPS-Cii-1801
ENSCING00000001704.3
F6UJB5
9
LLPS-Cii-1870
ENSCING00000022368.1
H2XYK0
10
LLPS-Cii-2170
ENSCING00000001978.3
F6X4A8
11
LLPS-Cii-2232
ENSCING00000013861.2
F6QG58
12
LLPS-Cii-2344
ENSCING00000002851.3
F6TN93
13
LLPS-Cii-0694
ENSCING00000003901.3
F6SN27
LOC100181797
14
LLPS-Cii-2221
ENSCING00000011397.2
A0A1W2WQI1
LOC100183014
15
LLPS-Cii-1441
ENSCING00000007326.3
F6YK29
LOC100184967
16
LLPS-Cii-0868
ENSCING00000004243.3
F6YG96
LOC100187385
17
LLPS-Cii-0556
ENSCING00000001800.3
F6X5P6
LOC108949611