Chondrus crispus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chc-0741
CHC_T00000161001
R7QN31
CHC_T00000161001
2
LLPS-Chc-0344
CHC_T00000312001
R7QN42
CHC_T00000312001
3
LLPS-Chc-0527
CHC_T00000588001
R7QL61
CHC_T00000588001
4
LLPS-Chc-0035
CHC_T00002510001
R7Q7B8
CHC_T00002510001
5
LLPS-Chc-0405
CHC_T00003130001
R7QAD7
CHC_T00003130001
6
LLPS-Chc-1161
CHC_T00004107001
R7QBZ1
CHC_T00004107001
7
LLPS-Chc-1210
CHC_T00007476001
R7QT73
CHC_T00007476001
8
LLPS-Chc-0375
CHC_T00007501001
R7QRU6
CHC_T00007501001
9
LLPS-Chc-0763
CHC_T00007775001
R7QV70
CHC_T00007775001
10
LLPS-Chc-1154
CHC_T00008637001
R7QRS8
CHC_T00008637001
11
LLPS-Chc-0877
CHC_T00009433001
R7QPH9
CHC_T00009433001
12
LLPS-Chc-0677
CHC_T00010059001
R7Q7R1
CHC_T00010059001
13
LLPS-Chc-0723
CHC_465
M5DDG1
rps7