Cercocebus atys      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cea-1751
ENSCATG00000020336.1
A0A2K5L0N0
2
LLPS-Cea-2983
ENSCATG00000030233.1
A0A2K5LGQ1
3
LLPS-Cea-3660
ENSCATG00000040859.1
A0A2K5NEX0
4
LLPS-Cea-2561
ENSCATG00000033744.1
A0A2K5M413
AARS2
5
LLPS-Cea-2683
ENSCATG00000032831.1
A0A2K5LY95
DARS2
6
LLPS-Cea-0541
ENSCATG00000043684.1
A0A2K5NXS4
DHX30
7
LLPS-Cea-4797
ENSCATG00000041378.1
A0A2K5NID3
ERAL1
8
LLPS-Cea-1715
ENSCATG00000042475.1
A0A2K5NQD5
FASTK
9
LLPS-Cea-0727
ENSCATG00000031285.1
A0A2K5LNI9
FASTKD1
10
LLPS-Cea-1483
ENSCATG00000038647.1
A0A2K5N0I0
FASTKD2
11
LLPS-Cea-3140
ENSCATG00000035808.1
A0A2K5MHJ1
GRSF1
12
LLPS-Cea-1745
ENSCATG00000034820.1
A0A2K5MB01
HSD17B10
13
LLPS-Cea-4499
ENSCATG00000035710.1
A0A2K5MGP2
MCU
14
LLPS-Cea-1165
ENSCATG00000034688.1
A0A2K5MB31
ME2
15
LLPS-Cea-0951
ENSCATG00000041516.1
A0A2K5NJG9
MRM1
16
LLPS-Cea-1313
ENSCATG00000029383.1
A0A2K5LB93
MRM2
17
LLPS-Cea-1274
ENSCATG00000032099.1
A0A2K5LTN3
MRM3
18
LLPS-Cea-1136
ENSCATG00000031286.1
A0A2K5LNN1
MRPL19
19
LLPS-Cea-0474
ENSCATG00000045001.1
A0A2K5P617
MRPL43
20
LLPS-Cea-4758
ENSCATG00000034419.1
A0A2K5M896
MRPS27
21
LLPS-Cea-0888
ENSCATG00000030049.1
A0A2K5LFC9
MRPS31
22
LLPS-Cea-0804
ENSCATG00000045102.1
A0A2K5P6R2
MRPS7
23
LLPS-Cea-3229
ENSCATG00000036678.1
A0A2K5MMU8
MRPS9
24
LLPS-Cea-4497
ENSCATG00000012833.1
A0A2K5KRC9
MTERF3
25
LLPS-Cea-1307
ENSCATG00000035677.1
A0A2K5MGL6
MTPAP
26
LLPS-Cea-4334
ENSCATG00000044366.1
A0A2K5P1V4
NLRX1
27
LLPS-Cea-2144
ENSCATG00000008000.1
A0A2K5KM31
NOA1
28
LLPS-Cea-1809
ENSCATG00000041339.1
A0A2K5NID0
PMPCB
29
LLPS-Cea-0689
ENSCATG00000031551.1
A0A2K5LQU1
PNPT1
30
LLPS-Cea-1950
ENSCATG00000040393.1
A0A2K5NBX7
POLRMT
31
LLPS-Cea-3995
ENSCATG00000019069.1
A0A2K5KZB8
PTCD2
32
LLPS-Cea-2345
ENSCATG00000036939.1
A0A2K5MPF8
RPUSD3
33
LLPS-Cea-3283
ENSCATG00000041570.1
A0A2K5NJL0
RPUSD4
34
LLPS-Cea-3119
ENSCATG00000015873.1
A0A2K5KVH3
SUCLG2
35
LLPS-Cea-3312
ENSCATG00000030043.1
A0A2K5LFB1
SUPV3L1
36
LLPS-Cea-4397
ENSCATG00000009009.1
A0A2K5KMR2
TFB1M
37
LLPS-Cea-0118
ENSCATG00000038234.1
A0A2K5MXT3
TRUB2
38
LLPS-Cea-3104
ENSCATG00000031735.1
A0A2K5LRD5
TWNK
39
LLPS-Cea-1214
ENSCATG00000041095.1
A0A2K5NGZ0
YME1L1