Beauveria bassiana      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Beb-0740
BB8028_0004g03040
2
LLPS-Beb-0157
BB8028_0008g00550
A0A2N6P2D6
cyt-5
3
LLPS-Beb-1202
BB8028_0002g05330
A0A2N6NU05
HSD17B10
4
LLPS-Beb-0999
BB8028_0004g03510
A0A2N6NYV7
MRM1
5
LLPS-Beb-0522
BB8028_0003g03070
A0A2N6NKU6
mrp-9
6
LLPS-Beb-0320
BB8028_0002g13310
A0A2N6NEX2
MRPL4
7
LLPS-Beb-0972
BB8028_0003g11570
A0A2N6NQX5
MRPL51
8
LLPS-Beb-0196
BB8028_0001g06050
A0A2N6NZZ6
msd1
9
LLPS-Beb-0984
BB8028_0001g17430
A0A2N6NHU1
suv3
10
LLPS-Beb-1015
BB8028_0001g03670
A0A2N6NZC2
YME1