Ictalurus punctatus      Microtubule


※ Microtubule introduction

    Microtubules (MTs) are tubulin heterodimers that are arranged in a parallel shape of hollow cylinders which play roles in regulating the mechanical structure and dynamics of cells. Much of the structure and dynamics of MTs is highly ordered (1). In fact, microtubules were enable to be used as platforms to understand the mechanisms underlying liquid–liquid phase separation, some RNA binding proteins on microtubules leads to the formation of mRNA-rich liquid-like compartments on microtubules (2).

Reference
1. Ilan, Y. (2019) Randomness in microtubule dynamics: an error that requires correction or an inherent plasticity required for normal cellular function? Cell Biol Int, PMID: 31042006
2. Maucuer, A., Desforges, B., Joshi, V., Boca, M., Kretov, D. A., Hamon, L., et al. (2018) Microtubules as platforms for probing liquid-liquid phase separation in cells - application to RNA-binding proteins. J Cell Sci, 131(11). PMID: 29728455


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Icp-1801
ENSIPUG00000012754.1
A0A2D0PIZ8
LOC108255233
2
LLPS-Icp-0453
ENSIPUG00000008876.1
A0A2D0SI67
LOC108275580
3
LLPS-Icp-1807
ENSIPUG00000001227.1
W5UB27
POC1A
4
LLPS-Icp-3945
ENSIPUG00000013524.1
A0A2D0RJP1
poc1b