Astyanax mexicanus      Microtubule


※ Microtubule introduction

    Microtubules (MTs) are tubulin heterodimers that are arranged in a parallel shape of hollow cylinders which play roles in regulating the mechanical structure and dynamics of cells. Much of the structure and dynamics of MTs is highly ordered (1). In fact, microtubules were enable to be used as platforms to understand the mechanisms underlying liquid–liquid phase separation, some RNA binding proteins on microtubules leads to the formation of mRNA-rich liquid-like compartments on microtubules (2).

Reference
1. Ilan, Y. (2019) Randomness in microtubule dynamics: an error that requires correction or an inherent plasticity required for normal cellular function? Cell Biol Int, PMID: 31042006
2. Maucuer, A., Desforges, B., Joshi, V., Boca, M., Kretov, D. A., Hamon, L., et al. (2018) Microtubules as platforms for probing liquid-liquid phase separation in cells - application to RNA-binding proteins. J Cell Sci, 131(11). PMID: 29728455


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asm-0226
ENSAMXG00000031614.1
A0A3B1ING2
2
LLPS-Asm-1650
ENSAMXG00000021280.2
W5LPS2
3
LLPS-Asm-2214
ENSAMXG00000031158.1
A0A3B1J181
4
LLPS-Asm-3877
ENSAMXG00000024703.2
W5LRA2
5
LLPS-Asm-2377
ENSAMXG00000011656.2
W5KWM0
POC1B