Rhinopithecus bieti      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Rhb-1675
ENSRBIG00000032244.1
A0A2K6KYR6
BAHCC1
2
LLPS-Rhb-3265
ENSRBIG00000017037.1
A0A2K6JX20
CASP8AP2
3
LLPS-Rhb-0988
ENSRBIG00000044907.1
A0A2K6N680
CPSF1
4
LLPS-Rhb-0074
ENSRBIG00000044792.1
A0A2K6N5D3
CPSF2
5
LLPS-Rhb-0732
ENSRBIG00000041615.1
A0A2K6MJV7
CPSF3
6
LLPS-Rhb-2152
ENSRBIG00000033886.1
A0A2K6L8D0
CPSF4
7
LLPS-Rhb-2946
ENSRBIG00000034739.1
A0A2K6LDG4
CTCF
8
LLPS-Rhb-2584
ENSRBIG00000044347.1
A0A2K6N260
CTR9
9
LLPS-Rhb-0383
ENSRBIG00000030629.1
A0A2K6KPP1
DDX20
10
LLPS-Rhb-2162
ENSRBIG00000042397.1
A0A2K6MPV5
FIP1L1
11
LLPS-Rhb-1846
ENSRBIG00000028954.1
A0A2K6KG57
H2AFV
12
LLPS-Rhb-2230
ENSRBIG00000035653.1
A0A2K6LIX6
HINFP
13
LLPS-Rhb-2856
ENSRBIG00000001561.1
A0A2K6JMP3
LSM10
14
LLPS-Rhb-1575
ENSRBIG00000040079.1
A0A2K6M9Y9
LSM11
15
LLPS-Rhb-2734
ENSRBIG00000036504.1
A0A2K6LNZ7
NPAT
16
LLPS-Rhb-2109
ENSRBIG00000040963.1
A0A2K6MFS7
SYMPK
17
LLPS-Rhb-0707
ENSRBIG00000038164.1
A0A2K6LYM5
TP53