Ornithorhynchus anatinus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 16 genes.  Reviewed (0 or Unreviewed (16

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ora-0020
ENSOANG00000029921.1
K7ECD3
2
LLPS-Ora-0240
ENSOANG00000004762.2
F7FUW2
3
LLPS-Ora-0392
ENSOANG00000000255.1
F6YUG3
4
LLPS-Ora-0505
ENSOANG00000006567.2
F6WFW2
5
LLPS-Ora-0634
ENSOANG00000003384.3
F7BMQ4
6
LLPS-Ora-0892
ENSOANG00000005073.1
F6PG15
7
LLPS-Ora-2036
ENSOANG00000008926.2
F7D2Y4
CASP8AP2
8
LLPS-Ora-1570
ENSOANG00000010716.1
F6RG92
CPSF1
9
LLPS-Ora-1360
ENSOANG00000003822.2
F6T6L1
CPSF2
10
LLPS-Ora-1695
ENSOANG00000008577.3
F6PHY6
CPSF3
11
LLPS-Ora-1854
ENSOANG00000007729.2
F6PXL2
CPSF4
12
LLPS-Ora-1126
ENSOANG00000003318.2
F7AEF2
DDX20
13
LLPS-Ora-2547
ENSOANG00000009378.2
F7FEF1
H2AFV
14
LLPS-Ora-2698
ENSOANG00000006444.2
F6VMT9
LOC100080465
15
LLPS-Ora-2141
ENSOANG00000030706.1
K7EE98
LOC103169995
16
LLPS-Ora-1451
ENSOANG00000002066.1
F6ZWR5
LSM10