Mesocricetus auratus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mea-0535
ENSMAUG00000000166.1
2
LLPS-Mea-0704
ENSMAUG00000021253.1
3
LLPS-Mea-2599
ENSMAUG00000010526.1
4
LLPS-Mea-4097
ENSMAUG00000018908.1
5
LLPS-Mea-2631
ENSMAUG00000018512.1
A0A1U7QU01
Casp8ap2
6
LLPS-Mea-1581
ENSMAUG00000003601.1
A0A1U7QU45
Cpsf1
7
LLPS-Mea-0899
ENSMAUG00000015160.1
A0A1U8BJJ1
Cpsf2
8
LLPS-Mea-1487
ENSMAUG00000011685.1
A0A1U8CCQ0
Ctcf
9
LLPS-Mea-1759
ENSMAUG00000016366.1
A0A1U7QK98
Ctr9
10
LLPS-Mea-0268
ENSMAUG00000010659.1
A0A1U7QLR1
Ddx20
11
LLPS-Mea-2770
ENSMAUG00000003103.1
A0A1U8BYM0
Hinfp
12
LLPS-Mea-3842
ENSMAUG00000011129.1
A0A1U8BQR8
LOC101834176
13
LLPS-Mea-0355
ENSMAUG00000004789.1
A0A1U7RGH9
LOC101837114
14
LLPS-Mea-0784
ENSMAUG00000016624.1
A0A1U8CSD3
Lsm10
15
LLPS-Mea-0005
ENSMAUG00000016249.1
A0A1U7Q7M4
Lsm11
16
LLPS-Mea-3721
ENSMAUG00000015657.1
A0A1U7R2V5
Sympk
17
LLPS-Mea-2176
ENSMAUG00000022241.1
Q00366
TP53