Macaca mulatta      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 15 genes.  Reviewed (0 or Unreviewed (15

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mam-0456
ENSMMUG00000018984.3
F6XXA0
BAHCC1
2
LLPS-Mam-4145
ENSMMUG00000009182.3
F7HPB6
CASP8AP2
3
LLPS-Mam-2503
ENSMMUG00000007380.3
H9FTK0
CPSF1
4
LLPS-Mam-2280
ENSMMUG00000000699.3
F6YTM3
CPSF2
5
LLPS-Mam-1806
ENSMMUG00000018038.3
A0A1D5RHC8
CPSF3
6
LLPS-Mam-2619
ENSMMUG00000019191.3
F7BI49
CPSF4
7
LLPS-Mam-1147
ENSMMUG00000009798.3
G7NQ61
CTCF
8
LLPS-Mam-3584
ENSMMUG00000011438.3
F7B9X6
CTR9
9
LLPS-Mam-1629
ENSMMUG00000009987.3
F6QUE3
GON4L
10
LLPS-Mam-0086
ENSMMUG00000000962.3
H9EMQ0
H2AFV
11
LLPS-Mam-2093
ENSMMUG00000014877.3
F6TXD2
HINFP
12
LLPS-Mam-1754
ENSMMUG00000017338.3
F7HBM2
LSM10
13
LLPS-Mam-1431
ENSMMUG00000004157.3
F6XC89
NPAT
14
LLPS-Mam-0096
ENSMMUG00000015428.3
I0FJW9
SYMPK
15
LLPS-Mam-4165
ENSMMUG00000008639.3
P56424
TP53