Ictidomys tridecemlineatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ict-2243
ENSSTOG00000021534.2
I3N2T8
BAHCC1
2
LLPS-Ict-2458
ENSSTOG00000023968.2
I3N296
CASP8AP2
3
LLPS-Ict-0590
ENSSTOG00000009957.3
I3MEM3
CPSF1
4
LLPS-Ict-3544
ENSSTOG00000009528.3
I3MDQ4
CPSF2
5
LLPS-Ict-2023
ENSSTOG00000004476.3
I3M4C1
CPSF3
6
LLPS-Ict-1831
ENSSTOG00000001688.3
A0A287D9Y7
CPSF4
7
LLPS-Ict-2757
ENSSTOG00000024951.2
I3MZ84
CTCF
8
LLPS-Ict-1182
ENSSTOG00000013594.3
I3MLB4
CTR9
9
LLPS-Ict-0431
ENSSTOG00000029089.2
I3N9G4
DDX20
10
LLPS-Ict-3778
ENSSTOG00000012166.3
I3MIP2
FIP1L1
11
LLPS-Ict-1618
ENSSTOG00000004664.3
A0A287D7R9
Gon4l
12
LLPS-Ict-1391
ENSSTOG00000011533.3
A0A287D335
H2AFV
13
LLPS-Ict-3150
ENSSTOG00000014457.3
A0A287D3P4
HINFP
14
LLPS-Ict-1896
ENSSTOG00000000606.3
I3LX07
LSM10
15
LLPS-Ict-3253
ENSSTOG00000004382.3
A0A287CY64
NPAT
16
LLPS-Ict-2735
ENSSTOG00000001534.3
I3LYS1
SYMPK
17
LLPS-Ict-3099
ENSSTOG00000022774.2
I3N5N2
TP53