Galdieria sulphuraria      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gas-0837
Gasu_05520
M2XPJ7
Gasu_05520
2
LLPS-Gas-0873
Gasu_10260
M2X575
Gasu_10260
3
LLPS-Gas-0916
Gasu_15470
M2Y5S4
Gasu_15470
4
LLPS-Gas-0015
Gasu_29090
M2W1X7
Gasu_29090
5
LLPS-Gas-0553
Gasu_29890
M2XHI7
Gasu_29890
6
LLPS-Gas-1175
Gasu_53550
M2WSZ8
Gasu_53550
7
LLPS-Gas-0555
Gasu_58850
M2X9H3
Gasu_58850