Chlamydomonas reinhardtii      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chr-0956
CHLRE_02g099200v5
A0A2K3E241
CHLRE_02g099200v5
2
LLPS-Chr-1076
CHLRE_03g189605v5
A0A2K3DY83
CHLRE_03g189605v5
3
LLPS-Chr-1420
CHLRE_10g432700v5
A0A2K3D9Z0
CHLRE_10g432700v5
4
LLPS-Chr-0713
CHLRE_12g487600v5
A0A2K3D2B0
CHLRE_12g487600v5
5
LLPS-Chr-1052
CHLRE_12g498050v5
A0A2K3D3G0
CHLRE_12g498050v5
6
LLPS-Chr-0782
CHLRE_13g567700v5
A8HRZ9
CHLRE_13g567700v5
7
LLPS-Chr-1040
CHLRE_13g573450v5
A0A2K3CZU5
CHLRE_13g573450v5
8
LLPS-Chr-0390
CHLRE_24g755647v5
A0A2K3CN33
CHLRE_24g755647v5