Aotus nancymaae      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aon-1644
ENSANAG00000018759.1
A0A2K5C1I6
2
LLPS-Aon-2287
ENSANAG00000030513.1
A0A2K5DXG0
3
LLPS-Aon-2859
ENSANAG00000031489.1
A0A2K5E2D0
4
LLPS-Aon-4482
ENSANAG00000035276.1
A0A2K5EQM5
BAHCC1
5
LLPS-Aon-1457
ENSANAG00000021679.1
A0A2K5CET9
CASP8AP2
6
LLPS-Aon-1566
ENSANAG00000036514.1
A0A2K5EY40
CPSF1
7
LLPS-Aon-2175
ENSANAG00000022915.1
A0A2K5CMF7
CPSF2
8
LLPS-Aon-1610
ENSANAG00000031254.1
A0A2K5E1M3
CPSF3
9
LLPS-Aon-1343
ENSANAG00000021360.1
A0A2K5CD84
CPSF4
10
LLPS-Aon-2267
ENSANAG00000027330.1
A0A2K5DDI1
CTCF
11
LLPS-Aon-3641
ENSANAG00000038032.1
A0A2K5F7Q1
CTR9
12
LLPS-Aon-0909
ENSANAG00000037881.1
A0A2K5F6N4
DDX20
13
LLPS-Aon-2706
ENSANAG00000032461.1
A0A2K5EAV0
FIP1L1
14
LLPS-Aon-1152
ENSANAG00000036572.1
A0A2K5EYF7
GON4L
15
LLPS-Aon-3941
ENSANAG00000021764.1
A0A2K5CFP6
H2AFV
16
LLPS-Aon-0226
ENSANAG00000030158.1
A0A2K5DVB5
HINFP
17
LLPS-Aon-2601
ENSANAG00000024748.1
A0A2K5CY99
NPAT
18
LLPS-Aon-0940
ENSANAG00000021087.1
A0A2K5CDJ4
SYMPK