Anas platyrhynchos      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 14 genes.  Reviewed (0 or Unreviewed (14

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anp-1757
ENSAPLG00000010033.1
U3IR70
2
LLPS-Anp-3067
ENSAPLG00000014802.1
U3J563
3
LLPS-Anp-1889
ENSAPLG00000002243.1
U3I398
CASP8AP2
4
LLPS-Anp-2874
ENSAPLG00000006330.1
U3IFF6
CPSF2
5
LLPS-Anp-0904
ENSAPLG00000006941.1
U3IH88
CPSF3
6
LLPS-Anp-0103
ENSAPLG00000006981.1
U3IH73
CPSF4
7
LLPS-Anp-2470
ENSAPLG00000007458.1
U3IIP3
CTCF
8
LLPS-Anp-2148
ENSAPLG00000005343.1
U3ICI5
CTR9
9
LLPS-Anp-1362
ENSAPLG00000003042.1
U3I5M0
FIP1L1
10
LLPS-Anp-0169
ENSAPLG00000003569.1
U3I726
H2AFZ
11
LLPS-Anp-0256
ENSAPLG00000014291.1
U3J3Q1
HINFP
12
LLPS-Anp-0922
ENSAPLG00000014097.1
U3J3E3
LOC101794688
13
LLPS-Anp-1648
ENSAPLG00000013714.1
U3J1Z6
LSM11
14
LLPS-Anp-1094
ENSAPLG00000014400.1
U3J426
NPAT