Xiphophorus maculatus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xim-0126
ENSXMAG00000012789.2
A0A3B5PVB8
2
LLPS-Xim-0646
ENSXMAG00000007573.2
M3ZZF4
3
LLPS-Xim-1048
ENSXMAG00000016713.2
M4AQK6
4
LLPS-Xim-1065
ENSXMAG00000002485.2
A0A3B5RBY3
5
LLPS-Xim-1342
ENSXMAG00000015538.2
A0A3B5PZG5
6
LLPS-Xim-1382
ENSXMAG00000019556.2
M4AYQ8
7
LLPS-Xim-1477
ENSXMAG00000001521.2
A0A3B5R0P4
8
LLPS-Xim-1884
ENSXMAG00000029016.1
A0A3B5QKE9
9
LLPS-Xim-1975
ENSXMAG00000009532.2
M4A516
10
LLPS-Xim-2099
ENSXMAG00000026315.1
A0A3B5Q8S9
11
LLPS-Xim-2976
ENSXMAG00000014191.2
M4AIB6