Ostreococcus lucimarinus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Osl-1380
OSTLU_26050
A4S3G8
OSTLU_26050
2
LLPS-Osl-0468
OSTLU_30722
A4RUS4
OSTLU_30722
3
LLPS-Osl-0414
OSTLU_33696
A4S371
OSTLU_33696
4
LLPS-Osl-1443
OSTLU_40865
A4RYJ1
OSTLU_40865
5
LLPS-Osl-0945
OSTLU_7191
A4RXM0
OSTLU_7191