Macaca fascicularis      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Maf-1117
ENSMFAG00000031794.1
2
LLPS-Maf-2129
ENSMFAG00000000987.1
3
LLPS-Maf-4473
ENSMFAG00000000059.1
4
LLPS-Maf-2125
ENSMFAG00000031755.1
G7NW60
EGM_00945
5
LLPS-Maf-0968
ENSMFAG00000037363.1
G7PSY4
EGM_07214
6
LLPS-Maf-0578
ENSMFAG00000030305.1
G7PXW0
EGM_09856
7
LLPS-Maf-0316
ENSMFAG00000039824.1
G7PY61
EGM_09962
8
LLPS-Maf-0877
ENSMFAG00000014362.1
G7NYH9
EGM_10761
9
LLPS-Maf-3887
ENSMFAG00000031523.1
G7P7P2
EGM_15124
10
LLPS-Maf-1106
ENSMFAG00000032027.1
G7P6Q3
EGM_15587
11
LLPS-Maf-1471
ENSMFAG00000002750.1
G8F4K2
EGM_20453
12
LLPS-Maf-1999
ENSMFAG00000035412.1
G7PM22
GEMIN6