Gasterosteus aculeatus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gaa-0135
ENSGACG00000009619.1
G3P514
2
LLPS-Gaa-0227
ENSGACG00000014592.1
G3PNS0
3
LLPS-Gaa-0413
ENSGACG00000005286.1
G3NNS9
4
LLPS-Gaa-0427
ENSGACG00000020825.1
G3QCB6
5
LLPS-Gaa-0563
ENSGACG00000010584.1
G3P8S9
6
LLPS-Gaa-1413
ENSGACG00000012444.1
G3PFT7
7
LLPS-Gaa-1803
ENSGACG00000000448.2
G3N5K7
8
LLPS-Gaa-1822
ENSGACG00000005362.1
G3NP18
9
LLPS-Gaa-2370
ENSGACG00000001120.1
G3N824
10
LLPS-Gaa-2721
ENSGACG00000012164.1
G3PET4