Pan paniscus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pap-1835
ENSPPAG00000033158.1
A0A2R9AR87
2
LLPS-Pap-1837
ENSPPAG00000029837.1
A0A2R9ACX5
3
LLPS-Pap-1192
ENSPPAG00000027747.1
A0A2R9A1D8
ATM
4
LLPS-Pap-3860
ENSPPAG00000042807.1
A0A2R9CEN3
ATR
5
LLPS-Pap-0063
ENSPPAG00000029090.1
A0A2R9A818
FUS
6
LLPS-Pap-0264
ENSPPAG00000032363.1
A0A2R9AMJ5
HDAC1
7
LLPS-Pap-2488
ENSPPAG00000029994.1
A0A2R9A952
PRKDC
8
LLPS-Pap-2883
ENSPPAG00000041687.1
A0A2R9CAL1
RAD51
9
LLPS-Pap-4170
ENSPPAG00000026278.1
A0A2R8ZQE4
RBM45
10
LLPS-Pap-0336
ENSPPAG00000040055.1
A0A2R9BY74
TP53BP1