Oreochromis niloticus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orn-0144
ENSONIG00000001629.1
I3IZK4
2
LLPS-Orn-0729
ENSONIG00000005496.1
I3JDG6
3
LLPS-Orn-2068
ENSONIG00000000770.1
I3IWI2
4
LLPS-Orn-3776
ENSONIG00000005609.1
I3JDW9
atmin
5
LLPS-Orn-1804
ENSONIG00000021363.1
I3KZW8
LOC100693699
6
LLPS-Orn-1203
ENSONIG00000004883.1
I3JBA1
prkdc
7
LLPS-Orn-3754
ENSONIG00000008512.1
I3JPA7
rad50
8
LLPS-Orn-2413
ENSONIG00000001450.1
I3IYY3
rbm45
9
LLPS-Orn-2490
ENSONIG00000007015.1
I3JJ06
tp53bp1