Gallus gallus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gaga-0483
ENSGALG00000042469.3
2
LLPS-Gaga-1042
ENSGALG00000045705.2
3
LLPS-Gaga-3205
ENSGALG00000032219.2
A0A1D5PPI6
4
LLPS-Gaga-3396
ENSGALG00000017159.7
E1C0Q6
ATM
5
LLPS-Gaga-2030
ENSGALG00000040475.3
A0A1D5P9S8
ATMIN
6
LLPS-Gaga-3050
ENSGALG00000002663.6
F1NGW1
ATR
7
LLPS-Gaga-0417
ENSGALG00000003297.7
P56517
HDAC1
8
LLPS-Gaga-3465
ENSGALG00000006794.6
F1NEG1
RAD50
9
LLPS-Gaga-2504
ENSGALG00000030313.3
P37383
RAD51A
10
LLPS-Gaga-3835
ENSGALG00000009202.5
F1NEX8
RBM45
11
LLPS-Gaga-0149
ENSGALG00000042201.3
A0A1D5P3K1
TP53BP1