Ciona intestinalis      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cii-0483
ENSCING00000020168.1
H2Y1J7
2
LLPS-Cii-0763
ENSCING00000021300.1
H2XN24
3
LLPS-Cii-0770
ENSCING00000023900.1
H2Y3C6
4
LLPS-Cii-1682
ENSCING00000000816.3
F6RJ65
5
LLPS-Cii-0886
ENSCING00000002649.3
F6YDI9
LOC100186761