Chlamydomonas reinhardtii      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chr-0362
CHLRE_09g397327v5
A0A2K3DEN6
CHLRE_09g397327v5
2
LLPS-Chr-1388
CHLRE_10g467200v5
A0A2K3DCC3
CHLRE_10g467200v5
3
LLPS-Chr-1579
CHLRE_12g544050v5
A0A2K3D6P2
CHLRE_12g544050v5
4
LLPS-Chr-0209
CHLRE_13g564350v5
A0A2K3CZ56
CHLRE_13g564350v5
5
LLPS-Chr-0624
CHLRE_16g673150v5
A0A2K3CVL9
CHLRE_16g673150v5
6
LLPS-Chr-0041
CHLRE_14g622850v5
Q6Q242
RAD51