Astyanax mexicanus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asm-0097
ENSAMXG00000017999.2
W5LFE7
2
LLPS-Asm-0164
ENSAMXG00000007463.2
W5KJA7
3
LLPS-Asm-0779
ENSAMXG00000019920.2
W5LKZ2
4
LLPS-Asm-1284
ENSAMXG00000009544.2
A0A3B1IRI3
5
LLPS-Asm-1600
ENSAMXG00000037984.1
A0A3B1KAQ1
6
LLPS-Asm-1642
ENSAMXG00000013672.2
W5L2K2
7
LLPS-Asm-1818
ENSAMXG00000007058.2
W5KIE9
8
LLPS-Asm-2661
ENSAMXG00000014851.2
A0A3B1JQ60
9
LLPS-Asm-3060
ENSAMXG00000044124.1
A0A3B1J8Q0