Sarcophilus harrisii      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 88 genes.  Reviewed (0 or Unreviewed (88

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sah-0531
ENSSHAG00000002892.1
G3VJD0
2
LLPS-Sah-0839
ENSSHAG00000018021.1
G3X0Q6
3
LLPS-Sah-1127
ENSSHAG00000002702.1
G3VIP6
4
LLPS-Sah-1462
ENSSHAG00000015254.1
G3WRB3
5
LLPS-Sah-1752
ENSSHAG00000008762.1
G3W3Y4
6
LLPS-Sah-2090
ENSSHAG00000012868.1
G3WI25
7
LLPS-Sah-2800
ENSSHAG00000013616.1
G3WKN6
8
LLPS-Sah-3153
ENSSHAG00000007149.1
G3VYJ8
9
LLPS-Sah-3273
ENSSHAG00000007163.1
G3VYL4
10
LLPS-Sah-4127
ENSSHAG00000017307.1
G3WYA0
11
LLPS-Sah-2177
ENSSHAG00000012759.1
G3WHP9
ADAD2
12
LLPS-Sah-3240
ENSSHAG00000013447.1
G3WK27
AFAP1L2
13
LLPS-Sah-0371
ENSSHAG00000009593.1
G3W6U2
AGO2
14
LLPS-Sah-1908
ENSSHAG00000011703.1
G3WE34
AKAP4
15
LLPS-Sah-2050
ENSSHAG00000013338.1
G3WJP9
CASC3
16
LLPS-Sah-0418
ENSSHAG00000017132.1
G3WXP1
CNBP
17
LLPS-Sah-3878
ENSSHAG00000020435.1
G1FKC0
COX1
18
LLPS-Sah-1353
ENSSHAG00000009350.1
G3W5Z0
CTSB
19
LLPS-Sah-1636
ENSSHAG00000017202.1
G3WXX7
DCP1A
20
LLPS-Sah-0047
ENSSHAG00000002011.1
G3VGG0
DDX25
21
LLPS-Sah-2171
ENSSHAG00000009132.1
G3W574
DDX4
22
LLPS-Sah-2393
ENSSHAG00000012772.1
G3WHR4
DDX5
23
LLPS-Sah-1665
ENSSHAG00000008540.1
G3W358
DHX9
24
LLPS-Sah-1076
ENSSHAG00000012077.1
G3WFC6
DICER1
25
LLPS-Sah-2414
ENSSHAG00000006291.1
G3VVN4
EDC4
26
LLPS-Sah-0516
ENSSHAG00000004864.1
G3VQW3
EEF1A1
27
LLPS-Sah-0483
ENSSHAG00000015756.1
G3WT06
EIF4A1
28
LLPS-Sah-0210
ENSSHAG00000008442.1
G3W2V2
EIF4E
29
LLPS-Sah-2415
ENSSHAG00000008109.1
G3W1R9
ELAVL1
30
LLPS-Sah-1344
ENSSHAG00000017362.1
G3WYH3
ENO4
31
LLPS-Sah-2286
ENSSHAG00000001435.1
G3VEK7
EWSR1
32
LLPS-Sah-2212
ENSSHAG00000009211.1
G3W5H1
FYCO1
33
LLPS-Sah-0429
ENSSHAG00000010641.1
G3WAH0
GPX4
34
LLPS-Sah-1285
ENSSHAG00000017930.1
G3X0E5
HNRNPA2B1
35
LLPS-Sah-0783
ENSSHAG00000018204.1
G3X1D1
HNRNPH1
36
LLPS-Sah-1611
ENSSHAG00000005864.1
G3VU91
HNRNPM
37
LLPS-Sah-0824
ENSSHAG00000017356.1
G3WYG4
HNRNPU
38
LLPS-Sah-0727
ENSSHAG00000007999.1
G3W1D6
HSP90AA1
39
LLPS-Sah-3731
ENSSHAG00000017428.1
G3WYP7
HSP90AB1
40
LLPS-Sah-0788
ENSSHAG00000010408.1
G3W9P3
HSPA2
41
LLPS-Sah-0867
ENSSHAG00000001712.1
G3VFH0
ILF3
42
LLPS-Sah-1568
ENSSHAG00000017747.1
G3WZS4
IP6K1
43
LLPS-Sah-1433
ENSSHAG00000016646.1
G3WW03
LAMP1
44
LLPS-Sah-2025
ENSSHAG00000015776.1
G3WT29
LDHA
45
LLPS-Sah-0552
ENSSHAG00000003431.1
G3VL41
LOC100913560
46
LLPS-Sah-0278
ENSSHAG00000004638.1
G3VQ51
LOC100914020
47
LLPS-Sah-0660
ENSSHAG00000005285.1
G3VSB9
LOC100919671
48
LLPS-Sah-1507
ENSSHAG00000001919.1
G3VQV7
LOC111720951
49
LLPS-Sah-1320
ENSSHAG00000008286.1
G3W2C2
LYAR
50
LLPS-Sah-0945
ENSSHAG00000018323.1
G3X1T1
MAEL
51
LLPS-Sah-0384
ENSSHAG00000016136.1
G3WUA6
NEDD1
52
LLPS-Sah-3449
ENSSHAG00000018131.1
G3X140
ODF1
53
LLPS-Sah-0544
ENSSHAG00000016260.1
G3WUP5
PIWIL1
54
LLPS-Sah-2988
ENSSHAG00000018279.1
G3X1M6
PIWIL2
55
LLPS-Sah-0533
ENSSHAG00000001041.1
G3VDB2
PMPCB
56
LLPS-Sah-3537
ENSSHAG00000018023.1
G3X0Q8
PSIP1
57
LLPS-Sah-0594
ENSSHAG00000008478.1
G3W2Z0
RBM14
58
LLPS-Sah-0393
ENSSHAG00000018629.1
G3X2V4
RBM8A
59
LLPS-Sah-3593
ENSSHAG00000002465.1
G3VHY3
RNASE8
60
LLPS-Sah-4062
ENSSHAG00000005609.1
G3VTD8
RNF17
61
LLPS-Sah-0196
ENSSHAG00000006767.1
G3VX90
RPL11
62
LLPS-Sah-1098
ENSSHAG00000014549.1
G3WNW4
RPL23A
63
LLPS-Sah-1349
ENSSHAG00000008226.1
G3W253
RPL24
64
LLPS-Sah-1732
ENSSHAG00000018052.1
G3X0U3
RPS14
65
LLPS-Sah-0366
ENSSHAG00000000111.1
G3VAC1
RPS8
66
LLPS-Sah-2533
ENSSHAG00000010045.1
G3W8E0
SMG6
67
LLPS-Sah-3163
ENSSHAG00000008208.1
G3W232
SPERT
68
LLPS-Sah-4056
ENSSHAG00000002552.1
G3VI78
SRSF1
69
LLPS-Sah-0667
ENSSHAG00000010876.1
G3WBA5
SRSF3
70
LLPS-Sah-3848
ENSSHAG00000000643.1
G3VC15
STK31
71
LLPS-Sah-0747
ENSSHAG00000014311.1
G3WN19
TDRD1
72
LLPS-Sah-0345
ENSSHAG00000011994.1
G3WF21
TDRD3
73
LLPS-Sah-2681
ENSSHAG00000001552.1
G3VEY7
TDRD5
74
LLPS-Sah-0376
ENSSHAG00000016901.1
G3WWW0
TDRD6
75
LLPS-Sah-2001
ENSSHAG00000013742.1
G3WL41
TDRD9
76
LLPS-Sah-0146
ENSSHAG00000005473.1
G3VSY1
TEKT2
77
LLPS-Sah-0272
ENSSHAG00000007120.1
G3VYG1
TNPO1
78
LLPS-Sah-0723
ENSSHAG00000008811.1
G3W445
TNRC6A
79
LLPS-Sah-1913
ENSSHAG00000011585.1
G3WDP8
TOMM34
80
LLPS-Sah-1290
ENSSHAG00000008866.1
G3W4B0
TOP3B
81
LLPS-Sah-1435
ENSSHAG00000002437.1
G3VHV1
TRA2B
82
LLPS-Sah-3379
ENSSHAG00000003498.1
G3VLB6
TRPM5
83
LLPS-Sah-3935
ENSSHAG00000012002.1
G3WF32
TTC21B
84
LLPS-Sah-0243
ENSSHAG00000018117.1
G3X119
UBTD1
85
LLPS-Sah-1064
ENSSHAG00000014763.1
G3WPL8
VIM
86
LLPS-Sah-1613
ENSSHAG00000002548.1
G3VI74
VPS26A
87
LLPS-Sah-2743
ENSSHAG00000003156.1
G3VK89
VPS35
88
LLPS-Sah-1846
ENSSHAG00000007786.1
G3W0N5
YBX2