Loxodonta africana      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 98 genes.  Reviewed (0 or Unreviewed (98

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Loa-0063
ENSLAFG00000031195.1
G3UNM0
2
LLPS-Loa-0363
ENSLAFG00000030882.1
G3UBT6
3
LLPS-Loa-1077
ENSLAFG00000029730.1
G3SNF2
4
LLPS-Loa-1489
ENSLAFG00000032495.1
G3UKU6
5
LLPS-Loa-1624
ENSLAFG00000030680.1
G3UC39
6
LLPS-Loa-1802
ENSLAFG00000025973.1
G3U506
7
LLPS-Loa-2325
ENSLAFG00000027712.1
G3U4Z2
8
LLPS-Loa-2664
ENSLAFG00000027787.1
G3UAN8
9
LLPS-Loa-3072
ENSLAFG00000008132.2
G3T189
10
LLPS-Loa-2019
ENSLAFG00000012345.4
G3TVV9
ADAD1
11
LLPS-Loa-1361
ENSLAFG00000006071.2
G3SXG3
ADAD2
12
LLPS-Loa-2445
ENSLAFG00000006062.3
G3SXF5
AFAP1L2
13
LLPS-Loa-0458
ENSLAFG00000012905.4
G3TAB5
AGO2
14
LLPS-Loa-3858
ENSLAFG00000029253.1
G3U7Z4
AKAP4
15
LLPS-Loa-3821
ENSLAFG00000005746.3
G3SWU0
ASZ1
16
LLPS-Loa-1381
ENSLAFG00000000606.4
G3SM19
CASC3
17
LLPS-Loa-4176
ENSLAFG00000017699.3
G3TJE1
CD74
18
LLPS-Loa-0785
ENSLAFG00000002502.1
G3SQK8
CNBP
19
LLPS-Loa-1288
ENSLAFG00000007380.2
G3SZW4
CTSB
20
LLPS-Loa-3095
ENSLAFG00000006894.1
G3SZ22
CYCS
21
LLPS-Loa-1602
ENSLAFG00000005837.3
G3SX02
DCP1A
22
LLPS-Loa-1139
ENSLAFG00000002213.3
G3SQ19
DDX1
23
LLPS-Loa-3403
ENSLAFG00000000532.3
G3SLW5
DDX25
24
LLPS-Loa-0245
ENSLAFG00000005900.3
G3SX46
DDX4
25
LLPS-Loa-2815
ENSLAFG00000004461.2
G3SUB0
DDX5
26
LLPS-Loa-1426
ENSLAFG00000022058.2
G3UKE5
DHX9
27
LLPS-Loa-1055
ENSLAFG00000013632.3
G3TBP7
DICER1
28
LLPS-Loa-2231
ENSLAFG00000012385.4
G3T9B2
EDC4
29
LLPS-Loa-0162
ENSLAFG00000001107.2
G3SMZ2
EIF4A1
30
LLPS-Loa-1437
ENSLAFG00000015628.3
G3TFI8
EIF4A3
31
LLPS-Loa-2287
ENSLAFG00000002450.3
G3SQH0
EIF4E
32
LLPS-Loa-0899
ENSLAFG00000004219.3
G3STV1
ELAVL1
33
LLPS-Loa-3313
ENSLAFG00000012497.4
G3T9I2
ENO4
34
LLPS-Loa-0495
ENSLAFG00000015757.4
G3TFS8
EWSR1
35
LLPS-Loa-2018
ENSLAFG00000009285.2
G3T3F9
FABP9
36
LLPS-Loa-2017
ENSLAFG00000023274.2
G3U0X9
FYCO1
37
LLPS-Loa-0188
ENSLAFG00000006902.3
G3U7V6
HNRNPA2B1
38
LLPS-Loa-0354
ENSLAFG00000008612.3
G3T261
HNRNPDL
39
LLPS-Loa-2707
ENSLAFG00000000424.1
G3SLP8
HNRNPF
40
LLPS-Loa-0733
ENSLAFG00000015766.3
G3TFT2
HNRNPH1
41
LLPS-Loa-0653
ENSLAFG00000013603.3
G3TBM3
HNRNPM
42
LLPS-Loa-2529
ENSLAFG00000021377.2
G3TTY8
HNRNPU
43
LLPS-Loa-2226
ENSLAFG00000028485.1
G3TVD7
HSP90AB1
44
LLPS-Loa-0017
ENSLAFG00000011924.4
G3U9J9
IGF2BP3
45
LLPS-Loa-1483
ENSLAFG00000021667.2
G3TQG7
ILF3
46
LLPS-Loa-1974
ENSLAFG00000013133.3
G3TAR7
IP6K1
47
LLPS-Loa-0539
ENSLAFG00000011133.4
G3T6X9
LAMP1
48
LLPS-Loa-3241
ENSLAFG00000011307.4
G3T790
LOC100668729
49
LLPS-Loa-4565
ENSLAFG00000001918.3
G3TPI9
LOC100672957
50
LLPS-Loa-2482
ENSLAFG00000027198.1
G3T709
LOC100675119
51
LLPS-Loa-1947
ENSLAFG00000027621.1
G3TR59
LOC111752373
52
LLPS-Loa-1008
ENSLAFG00000016582.2
G3THA1
LYAR
53
LLPS-Loa-3228
ENSLAFG00000021470.2
G3TNX2
MAEL
54
LLPS-Loa-1514
ENSLAFG00000033284.1
Q9TA27
MT-CO1
55
LLPS-Loa-0542
ENSLAFG00000013061.4
G3TAL6
NCL
56
LLPS-Loa-1448
ENSLAFG00000006312.3
G3SXY3
NEDD1
57
LLPS-Loa-0448
ENSLAFG00000006099.2
G3UCE3
ODF1
58
LLPS-Loa-0207
ENSLAFG00000013994.2
G3TSN6
PABPC1
59
LLPS-Loa-0715
ENSLAFG00000013812.3
G3TC21
PIWIL1
60
LLPS-Loa-0973
ENSLAFG00000016420.3
G3TGZ3
PIWIL2
61
LLPS-Loa-4213
ENSLAFG00000014153.4
G3UAQ2
PMPCB
62
LLPS-Loa-3112
ENSLAFG00000013878.3
G3UAL4
PSIP1
63
LLPS-Loa-3793
ENSLAFG00000010441.3
G3T5M3
RANBP9
64
LLPS-Loa-3543
ENSLAFG00000017232.3
G3TIG9
RANGRF
65
LLPS-Loa-4051
ENSLAFG00000009086.3
G3TQ95
RBM14
66
LLPS-Loa-2077
ENSLAFG00000021886.2
G5E796
RBM8A
67
LLPS-Loa-2791
ENSLAFG00000030853.1
G3ULE7
RPL11
68
LLPS-Loa-1945
ENSLAFG00000013387.4
G3TB76
RPL23A
69
LLPS-Loa-1017
ENSLAFG00000013804.3
G3TC12
RPL24
70
LLPS-Loa-1360
ENSLAFG00000027596.1
G3UCL9
RPS8
71
LLPS-Loa-0205
ENSLAFG00000018634.4
G3TL75
SMG1
72
LLPS-Loa-0500
ENSLAFG00000001261.4
G3TYI5
SMG6
73
LLPS-Loa-2778
ENSLAFG00000011325.2
G3T7A2
SPERT
74
LLPS-Loa-2111
ENSLAFG00000025743.1
G3UJD2
SRSF1
75
LLPS-Loa-0282
ENSLAFG00000018193.3
G3TKA5
SRSF3
76
LLPS-Loa-1560
ENSLAFG00000009258.4
G3T3E2
STK31
77
LLPS-Loa-3066
ENSLAFG00000026920.1
G3U9G4
TDRD15
78
LLPS-Loa-0698
ENSLAFG00000002705.3
G3SR03
TDRD3
79
LLPS-Loa-1629
ENSLAFG00000015295.3
G3TEV7
TDRD5
80
LLPS-Loa-0561
ENSLAFG00000005989.4
G3UKQ3
TDRD7
81
LLPS-Loa-2273
ENSLAFG00000007580.4
G3T096
TDRD9
82
LLPS-Loa-0534
ENSLAFG00000017273.4
G3TIK1
TEKT2
83
LLPS-Loa-1886
ENSLAFG00000028197.1
G3U5I4
TEKT4
84
LLPS-Loa-0006
ENSLAFG00000011796.3
G3T870
TNPO1
85
LLPS-Loa-0917
ENSLAFG00000004209.4
G3STU5
TNRC6A
86
LLPS-Loa-2400
ENSLAFG00000003560.2
G3SSM5
TOMM34
87
LLPS-Loa-1317
ENSLAFG00000018671.3
G3TL95
TOP3B
88
LLPS-Loa-1864
ENSLAFG00000017165.3
G3UFI5
TRA2B
89
LLPS-Loa-1493
ENSLAFG00000029891.1
G3UD36
TRPM5
90
LLPS-Loa-4271
ENSLAFG00000010010.4
G3T4U0
TTC21B
91
LLPS-Loa-3476
ENSLAFG00000010656.2
G3T609
UBTD1
92
LLPS-Loa-3003
ENSLAFG00000014963.3
G3U647
UPF1
93
LLPS-Loa-2205
ENSLAFG00000008552.4
G3T223
USP9X
94
LLPS-Loa-0127
ENSLAFG00000018142.3
G3TK83
VIM
95
LLPS-Loa-3090
ENSLAFG00000000888.3
G3SMJ3
VPS26A
96
LLPS-Loa-3009
ENSLAFG00000001705.2
G3SP30
VPS35
97
LLPS-Loa-3878
ENSLAFG00000014006.3
G3TCE9
YBX2
98
LLPS-Loa-0846
ENSLAFG00000003538.3
G3SSL1
YTHDC2