Ciona intestinalis      Chromatoid body


※ Chromatoid body introduction

    A single large granule of nuage, presents in post-meiotic spermatids is called the chromatoid body (1). Multiple proteins and some mRNAs have been found to localized to the chromatoid body including mouse VASA homolog , tudor-domain containing 1 (TDRD1), tudor-domain containing 6 (TDRD6), and tudor-domain containing 7 (TDRD7) , transition protein 2 (Tnp2), RANBP9, as a known MVH interactor also localizes to it. Its formation is related to the coalescence of intermitochondrial cement granules. In fact, the formation of the chromatoid body is not required for microRNA biogenesis, but might be important for its action on target mRNAs (1). In mice, the chromatoid body is a structure resembles Gp, TDRD6 plays a role in establishing the body and the localization of piRNA pathway components to this body (2).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 30086300
2. Ma, L., Buchold, G. M., Greenbaum, M. P., Roy, A., Burns, K. H., Zhu, H., et al. (2009) GASZ is essential for male meiosis and suppression of retrotransposon expression in the male germline. PLoS Genet, 5(9), e1000635. PMID: 19730684


There are 46 genes.  Reviewed (0 or Unreviewed (46

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cii-0055
ENSCING00000014808.2
F6SWJ9
2
LLPS-Cii-0093
ENSCING00000002796.3
F6XMP8
3
LLPS-Cii-0131
ENSCING00000006851.3
F6ZXN6
4
LLPS-Cii-0151
ENSCING00000022501.1
H2XR02
5
LLPS-Cii-0159
ENSCING00000022087.1
H2Y3Q2
6
LLPS-Cii-0312
ENSCING00000001412.3
F6YS67
7
LLPS-Cii-0423
ENSCING00000012576.2
F6YNJ1
8
LLPS-Cii-0581
ENSCING00000021342.1
H2XRI7
9
LLPS-Cii-0645
ENSCING00000007703.3
F6ZID9
10
LLPS-Cii-0651
ENSCING00000005587.3
F6U3S7
11
LLPS-Cii-0667
ENSCING00000008383.3
F6XSF3
12
LLPS-Cii-0723
ENSCING00000006306.3
F6Q4K7
13
LLPS-Cii-0783
ENSCING00000009849.3
F6V8G3
14
LLPS-Cii-0852
ENSCING00000021399.1
H2XQK9
15
LLPS-Cii-0857
ENSCING00000008100.3
F6UHM2
16
LLPS-Cii-0914
ENSCING00000005502.3
F7BD94
17
LLPS-Cii-0961
ENSCING00000002637.3
F6YDR3
18
LLPS-Cii-1015
ENSCING00000004839.3
F6TZ23
19
LLPS-Cii-1046
ENSCING00000004199.3
F7B4V3
20
LLPS-Cii-1051
ENSCING00000010099.3
F6PIQ0
21
LLPS-Cii-1076
ENSCING00000007792.3
F6X3A4
22
LLPS-Cii-1080
ENSCING00000019779.1
H2XU69
23
LLPS-Cii-1154
ENSCING00000006789.3
F6VE75
24
LLPS-Cii-1236
ENSCING00000011663.2
F6X986
25
LLPS-Cii-1241
ENSCING00000018620.1
H2XQH7
26
LLPS-Cii-1528
ENSCING00000010126.3
F6ZX46
27
LLPS-Cii-1613
ENSCING00000006280.3
F6UBT3
28
LLPS-Cii-1913
ENSCING00000000589.3
F6Q0D8
29
LLPS-Cii-1960
ENSCING00000023805.1
H2XV25
30
LLPS-Cii-2119
ENSCING00000018451.1
H2XP77
31
LLPS-Cii-2288
ENSCING00000004147.3
F6UHH9
32
LLPS-Cii-1567
ENSCING00000007391.3
Q8T883
Ci-tektinB1
33
LLPS-Cii-1186
ENSCING00000003926.3
F7A5D0
cirgg1
34
LLPS-Cii-2318
ENSCING00000025226.1
Q8HIM9
COI
35
LLPS-Cii-1647
ENSCING00000024102.1
H2Y1N7
gpx_d
36
LLPS-Cii-2173
ENSCING00000010522.3
F6S2C6
LOC100176316
37
LLPS-Cii-1349
ENSCING00000007375.3
A0A1W2WNG5
LOC100176319
38
LLPS-Cii-1733
ENSCING00000003326.3
F6SNL0
LOC100177507
39
LLPS-Cii-0471
ENSCING00000005034.3
F6T9R1
LOC100178199
40
LLPS-Cii-1383
ENSCING00000018116.1
H2XK93
LOC100178835
41
LLPS-Cii-0332
ENSCING00000007910.3
F6ST44
LOC100179759
42
LLPS-Cii-0867
ENSCING00000000288.3
F6ZZJ8
LOC100180632
43
LLPS-Cii-1685
ENSCING00000013983.2
F6QAE6
LOC100182930
44
LLPS-Cii-1082
ENSCING00000019658.1
H2XTZ1
LOC100184986
45
LLPS-Cii-0592
ENSCING00000001070.3
F7B0Q2
LOC100185176
46
LLPS-Cii-1176
ENSCING00000005631.3
F7A9K4
tektinA1