Caenorhabditis elegans      Centrosome/Spindle pole body


※ Centrosome/Spindle pole body introduction

    A centrosome is a composite material comprising a pair of 200-nm-long barrel-shaped centrioles surrounded by a dynamic protein mass called the pericentriolar material (PCM), which organizes hundreds to thousands of microtubules that build and position the mitotic spindle in metazoans (1). The seemingly unstructured mitotic PCM provides most of the mass and microtubule nucleation capacity of the centrosome, Mitotic PCM could also be liquid like, the mitotic PCM first assembles through phase separation of SPD-5 molecules around the centrioles. Liquid–liquid phase separation of the SPD-5 scaffold followed by maturation into a gel could explain why mitotic PCM is both spherical and stable (1).

Reference
1. Woodruff, J. B., Hyman, A. A., & Boke, E. (2018) Organization and Function of Non-dynamic Biomolecular Condensates. Trends Biochem Sci, 43(2), 81-94. PMID: 29258725


There are 250 genes.  Reviewed (57 or Unreviewed (193

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cae-a185
WBGene00021012
2
LLPS-Cae-0355
WBGene00000098
G5EDL3
air-1
3
LLPS-Cae-0045
WBGene00000377
P41988
cct-1
4
LLPS-Cae-0105
WBGene00000390
Q05062
cdc-42
5
LLPS-Cae-0242
WBGene00000405
P34556
cdk-1
6
LLPS-Cae-1182
WBGene00000874
Q8WT44
cyk-3
7
LLPS-Cae-0082
WBGene00000962
Q19020
dhc-1
8
LLPS-Cae-0072
WBGene00001005
Q22799
dlc-1
9
LLPS-Cae-0317
WBGene00001017
E2JKZ0
dnc-1
10
LLPS-Cae-0221
WBGene00001018
Q09248
dnc-2
11
LLPS-Cae-0073
WBGene00001209
P34339
egl-45
12
LLPS-Cae-0039
WBGene00001746
Q9U2Q9
gsk-3
13
LLPS-Cae-0004
WBGene00002010
P11141
hsp-6
14
LLPS-Cae-0339
WBGene00002228
G5EBX0
klp-18
15
LLPS-Cae-0218
WBGene00002219
Q9XU12
klp-7
16
LLPS-Cae-2166
WBGene00019432
O44548
knl-2
17
LLPS-Cae-2096
WBGene00002994
P45970
lin-5
18
LLPS-Cae-0125
WBGene00003047
Q9NDC9
lis-1
19
LLPS-Cae-0158
WBGene00003154
Q9XXI9
mcm-2
20
LLPS-Cae-0115
WBGene00003156
Q95XQ8
mcm-4
21
LLPS-Cae-0258
WBGene00003157
Q21902
mcm-5
22
LLPS-Cae-0034
WBGene00003158
P34647
mcm-6
23
LLPS-Cae-0175
WBGene00003159
O16297
mcm-7
24
LLPS-Cae-0147
WBGene00003183
P34808
mei-1
25
LLPS-Cae-0308
WBGene00003788
Q22078
npp-2
26
LLPS-Cae-0133
WBGene00003901
Q09543
paa-1
27
LLPS-Cae-0007
WBGene00008338
P90783
pafo-1
28
LLPS-Cae-0293
WBGene00003918
Q17353
par-3
29
LLPS-Cae-0327
WBGene00003921
Q9NAN2
par-6
30
LLPS-Cae-2110
WBGene00004027
Q94131
pie-1
31
LLPS-Cae-0160
WBGene00004042
P34331
plk-1
32
LLPS-Cae-0159
WBGene00004085
Q9XW79
pph-4.1
33
LLPS-Cae-0025
WBGene00012348
O18178
pptr-1
34
LLPS-Cae-0078
WBGene00010556
Q21215
rack-1
35
LLPS-Cae-0207
WBGene00004302
O17915
ran-1
36
LLPS-Cae-0333
WBGene00011501
P34560
rmd-1
37
LLPS-Cae-0149
WBGene00004458
Q9GZH5
rpn-1
38
LLPS-Cae-0208
WBGene00004460
Q04908
rpn-3
39
LLPS-Cae-2127
WBGene00007710
O02217
rsa-1
40
LLPS-Cae-2152
WBGene00012972
G5EFV3
rsa-2
41
LLPS-Cae-0224
WBGene00007784
O17607
ruvb-1
42
LLPS-Cae-0051
WBGene00020687
Q9GZH2
ruvb-2
43
LLPS-Cae-2115
WBGene00004726
P34402
sas-4
44
LLPS-Cae-2135
WBGene00009385
Q20010
sas-5
45
LLPS-Cae-2150
WBGene00012888
O62479
sas-6
46
LLPS-Cae-0118
WBGene00004775
G5ED39
sep-1
47
LLPS-Cae-0282
WBGene00004807
G5ECU1
skr-1
48
LLPS-Cae-0056
WBGene00004888
P55853
smo-1
49
LLPS-Cae-2116
WBGene00004953
P91870
spd-2
50
LLPS-Cae-2117
WBGene00004955
P91349
spd-5
51
LLPS-Cae-0108
WBGene00011365
Q03605
T02C1.1
52
LLPS-Cae-2123
WBGene00006381
G5ECG0
tac-1
53
LLPS-Cae-0367
WBGene00006529
P34690
tba-2
54
LLPS-Cae-0130
WBGene00006540
P34475
tbg-1
55
LLPS-Cae-2125
WBGene00006988
Q9GT24
zyg-1
56
LLPS-Cae-0176
WBGene00006997
Q23529
zyg-12
57
LLPS-Cae-0079
WBGene00006994
G5EEM5
zyg-9
58
LLPS-Cae-1788
WBGene00011116
59
LLPS-Cae-2043
WBGene00010306
60
LLPS-Cae-1300
WBGene00000001
G5EDP9
aap-1
61
LLPS-Cae-0644
WBGene00000090
Q94125
age-1
62
LLPS-Cae-1370
WBGene00000092
Q19955
ags-3
63
LLPS-Cae-0311
WBGene00000099
O01427
air-2
64
LLPS-Cae-1215
WBGene00000102
Q17941
akt-1
65
LLPS-Cae-1161
WBGene00007010
P34552
alx-1
66
LLPS-Cae-1115
WBGene00000149
Q10651
apl-1
67
LLPS-Cae-1391
WBGene00000156
Q21227
apr-1
68
LLPS-Cae-1509
WBGene00000188
O45379
arl-3
69
LLPS-Cae-0471
WBGene00008107
O17666
aspm-1
70
LLPS-Cae-1112
WBGene00000227
Q9N3Q4
atm-1
71
LLPS-Cae-0497
WBGene00015126
P34256
B0303.4
72
LLPS-Cae-1192
WBGene00015250
U4PBQ7
B0546.3
73
LLPS-Cae-1076
WBGene00043992
Q5CZ52
bbs-4
74
LLPS-Cae-1712
WBGene00010974
Q21626
bbs-5
75
LLPS-Cae-0698
WBGene00000244
Q23049
bbs-8
76
LLPS-Cae-1946
WBGene00022251
Q95XD3
blos-2
77
LLPS-Cae-0572
WBGene00000257
G5ECF4
bmk-1
78
LLPS-Cae-1932
WBGene00000264
B6VQ60
brc-1
79
LLPS-Cae-0395
WBGene00015926
B1Q249
C17H11.6
80
LLPS-Cae-1933
WBGene00016171
Q95QU0
C27F2.10
81
LLPS-Cae-0790
WBGene00008039
Q03573
C40H1.3
82
LLPS-Cae-0295
WBGene00000383
P81299
cdc-14
83
LLPS-Cae-0402
WBGene00000388
P30634
cdc-25.3
84
LLPS-Cae-2017
WBGene00000389
Q21762
cdc-25.4
85
LLPS-Cae-0777
WBGene00015203
Q09437
cdk-11.1
86
LLPS-Cae-1643
WBGene00013765
Q9U2Y2
cdkr-3
87
LLPS-Cae-0782
WBGene00011318
Q22059
cdt-2
88
LLPS-Cae-1526
WBGene00000417
P42573
ced-3
89
LLPS-Cae-1015
WBGene00008422
Q18983
CELE_D2045.2
90
LLPS-Cae-0681
WBGene00017342
Q7JP67
CELE_F10D7.5
91
LLPS-Cae-1617
WBGene00018781
Q9N4J7
CELE_F54A3.2
92
LLPS-Cae-0515
WBGene00019237
H2L0C5
CELE_H24G06.1
93
LLPS-Cae-1535
WBGene00019298
U4PSA1
CELE_K02D7.1
94
LLPS-Cae-0477
WBGene00019766
U4PEB6
CELE_M4.1
95
LLPS-Cae-1597
WBGene00044281
Q21694
CELE_R04A9.7
96
LLPS-Cae-1760
WBGene00019911
O44747
CELE_R06A10.4
97
LLPS-Cae-1165
WBGene00020208
H2L0I8
CELE_T04C4.1
98
LLPS-Cae-1577
WBGene00011612
A4F324
CELE_T08D2.7
99
LLPS-Cae-1573
WBGene00020444
Q9UAX0
CELE_T12B3.1
100
LLPS-Cae-1711
WBGene00012337
Q23215
CELE_W07G4.3
101
LLPS-Cae-0675
WBGene00044345
Q2WF61
CELE_Y48G1C.12
102
LLPS-Cae-1349
WBGene00022268
Q9GUM1
CELE_Y73E7A.1
103
LLPS-Cae-1709
WBGene00014077
Q23595
CELE_ZK792.4
104
LLPS-Cae-1114
WBGene00000484
G5EGF0
che-2
105
LLPS-Cae-1013
WBGene00000498
Q9N3Z3
chk-1
106
LLPS-Cae-0504
WBGene00000499
Q9U1Y5
chk-2
107
LLPS-Cae-2021
WBGene00010839
Q21489
chl-1
108
LLPS-Cae-0376
WBGene00022854
G5ECQ8
cin-4
109
LLPS-Cae-0868
WBGene00000519
Q9U2D2
cku-70
110
LLPS-Cae-1798
WBGene00000520
Q21829
cku-80
111
LLPS-Cae-0803
WBGene00010796
P34531
clip-1
112
LLPS-Cae-0088
WBGene00000549
P32744
cls-2
113
LLPS-Cae-1599
WBGene00000552
O16305
cmd-1
114
LLPS-Cae-1884
WBGene00000813
Q9GS00
csn-1
115
LLPS-Cae-1018
WBGene00000814
O01422
csn-2
116
LLPS-Cae-0832
WBGene00000815
Q9N425
csn-3
117
LLPS-Cae-0625
WBGene00000816
Q9N359
csn-4
118
LLPS-Cae-1437
WBGene00000817
P91001
csn-5
119
LLPS-Cae-0962
WBGene00000818
Q95PZ0
csn-6
120
LLPS-Cae-0452
WBGene00017472
Q9NB31
cst-1
121
LLPS-Cae-1166
WBGene00016038
Q304D8
cst-2
122
LLPS-Cae-0427
WBGene00006424
Q20595
ctbp-1
123
LLPS-Cae-1345
WBGene00000836
Q17389
cul-1
124
LLPS-Cae-0955
WBGene00000915
Q18688
daf-21
125
LLPS-Cae-0805
WBGene00001095
P90831
dars-2
126
LLPS-Cae-1254
WBGene00000942
P19826
deb-1
127
LLPS-Cae-0744
WBGene00012352
Q9XUJ7
dkf-1
128
LLPS-Cae-1372
WBGene00001007
G5ED34
dli-1
129
LLPS-Cae-0772
WBGene00022118
Q9N4I1
dnc-5
130
LLPS-Cae-0753
WBGene00016074
Q95X82
dnsn-1
131
LLPS-Cae-1620
WBGene00012004
Q22752
dyrb-1
132
LLPS-Cae-0707
WBGene00020770
S6F527
eat-17
133
LLPS-Cae-0586
WBGene00012156
Q9XXA2
ebp-2
134
LLPS-Cae-0938
WBGene00013028
Q9XWW8
efhc-1
135
LLPS-Cae-1524
WBGene00001281
G5EG38
emb-27
136
LLPS-Cae-0765
WBGene00001358
Q19705
evl-20
137
LLPS-Cae-1004
WBGene00018218
O16264
F40A3.3
138
LLPS-Cae-1948
WBGene00017981
O16299
figl-1
139
LLPS-Cae-0635
WBGene00001510
Q09649
fzr-1
140
LLPS-Cae-0396
WBGene00001558
Q2V4S2
gdi-1
141
LLPS-Cae-1583
WBGene00008805
Q19467
git-1
142
LLPS-Cae-0821
WBGene00018017
Q19989
golg-2
143
LLPS-Cae-1504
WBGene00001748
P48727
gsp-2
144
LLPS-Cae-1608
WBGene00001834
O17695
hda-1
145
LLPS-Cae-0042
WBGene00001860
O01789
him-1
146
LLPS-Cae-0700
WBGene00001985
O02100
hop-1
147
LLPS-Cae-0408
WBGene00002005
P09446
hsp-1
148
LLPS-Cae-1848
WBGene00002011
P34328
hsp-12.2
149
LLPS-Cae-1886
WBGene00002036
G8JY81
hum-2
150
LLPS-Cae-0624
WBGene00022465
Q8TA52
ift-20
151
LLPS-Cae-1739
WBGene00017973
A8DYR7
ift-81
152
LLPS-Cae-0543
WBGene00002075
Q9BIB8
imb-1
153
LLPS-Cae-1683
WBGene00012466
Q9XXI1
ippk-1
154
LLPS-Cae-1919
WBGene00010736
G5ECX8
istr-1
155
LLPS-Cae-1159
WBGene00002202
P42168
kin-19
156
LLPS-Cae-1501
WBGene00002203
Q20471
kin-20
157
LLPS-Cae-1422
WBGene00002210
Q21017
kin-29
158
LLPS-Cae-1923
WBGene00002222
Q19633
klp-11
159
LLPS-Cae-0315
WBGene00002230
Q965T6
klp-20
160
LLPS-Cae-0735
WBGene00002694
P92199
let-502
161
LLPS-Cae-0270
WBGene00022500
H2L0I2
lfi-1
162
LLPS-Cae-1487
WBGene00003030
Q07292
lin-45
163
LLPS-Cae-1881
WBGene00012366
O18188
maea-1
164
LLPS-Cae-0861
WBGene00003132
Q9N593
mat-1
165
LLPS-Cae-1593
WBGene00003133
O18191
mat-2
166
LLPS-Cae-0685
WBGene00003155
Q9XVR7
mcm-3
167
LLPS-Cae-0843
WBGene00010420
G5ED60
mcrs-1
168
LLPS-Cae-0063
WBGene00003161
Q9NGT3
mdf-2
169
LLPS-Cae-1651
WBGene00003186
Q10664
mek-2
170
LLPS-Cae-0946
WBGene00011304
Q8I113
mnk-1
171
LLPS-Cae-2016
WBGene00009551
Q20186
mob-1
172
LLPS-Cae-1082
WBGene00020447
Q9UAX1
mob-3
173
LLPS-Cae-1602
WBGene00016238
P34349
mob-4
174
LLPS-Cae-1500
WBGene00013140
O18211
mop-25.2
175
LLPS-Cae-1424
WBGene00003401
P39745
mpk-1
176
LLPS-Cae-1341
WBGene00009944
Q20680
mtcu-2
177
LLPS-Cae-0521
WBGene00007114
Q17440
mttu-1
178
LLPS-Cae-1473
WBGene00009507
Q20129
mus-101
179
LLPS-Cae-0198
WBGene00003576
Q17635
ndc-80
180
LLPS-Cae-1540
WBGene00021461
A0A061AD48
nekl-1
181
LLPS-Cae-1056
WBGene00012344
P91917
ola-1
182
LLPS-Cae-2037
WBGene00012650
Q9XX17
orc-1
183
LLPS-Cae-0910
WBGene00003882
Q21037
orc-2
184
LLPS-Cae-0884
WBGene00013857
Q23249
orc-5
185
LLPS-Cae-2030
WBGene00003892
Q9XW70
osm-12
186
LLPS-Cae-1493
WBGene00003885
G5ED37
osm-5
187
LLPS-Cae-0950
WBGene00004052
Q9N5L4
parg-2
188
LLPS-Cae-0372
WBGene00003931
Q9TZC4
pat-4
189
LLPS-Cae-0507
WBGene00003967
Q9XUS3
pdr-1
190
LLPS-Cae-1520
WBGene00003980
O17772
pes-7
191
LLPS-Cae-1364
WBGene00022448
Q9N492
pinn-1
192
LLPS-Cae-1816
WBGene00004035
Q9U1S7
pkd-2
193
LLPS-Cae-0899
WBGene00004038
Q22070
plc-3
194
LLPS-Cae-1189
WBGene00004040
G5EDU3
pld-1
195
LLPS-Cae-0318
WBGene00004043
Q9N2L7
plk-2
196
LLPS-Cae-1167
WBGene00004044
Q20845
plk-3
197
LLPS-Cae-0936
WBGene00004056
Q8MXI4
pmk-2
198
LLPS-Cae-1178
WBGene00017064
P91198
ppfr-2
199
LLPS-Cae-1350
WBGene00004086
Q9XTT8
pph-4.2
200
LLPS-Cae-0729
WBGene00007554
A9UJN4
pptr-2
201
LLPS-Cae-1621
WBGene00004183
Q20443
prk-2
202
LLPS-Cae-0914
WBGene00004212
Q95QG4
ptl-1
203
LLPS-Cae-1248
WBGene00016197
Q09476
pxl-1
204
LLPS-Cae-1297
WBGene00018869
Q95ZS6
rfip-1
205
LLPS-Cae-0508
WBGene00004355
Q22307
rha-1
206
LLPS-Cae-1818
WBGene00006468
G5EFE1
rhgf-1
207
LLPS-Cae-2040
WBGene00006476
S6EZU2
rhgf-2
208
LLPS-Cae-1032
WBGene00007860
G5EFB9
rilp-1
209
LLPS-Cae-0781
WBGene00004393
G5EFQ5
rnt-1
210
LLPS-Cae-1153
WBGene00004466
O61742
rpn-10
211
LLPS-Cae-1485
WBGene00004459
Q18115
rpn-2
212
LLPS-Cae-0541
WBGene00004506
Q9XTT9
rpt-6
213
LLPS-Cae-1969
WBGene00011995
Q22744
rsf-1
214
LLPS-Cae-0542
WBGene00004719
Q19469
sad-1
215
LLPS-Cae-1304
WBGene00020427
P91441
sav-1
216
LLPS-Cae-1527
WBGene00018467
Q6AHQ8
sdpn-1
217
LLPS-Cae-1849
WBGene00004767
Q93794
sel-10
218
LLPS-Cae-1585
WBGene00004858
P45897
sma-4
219
LLPS-Cae-0472
WBGene00004873
B2FDA8
smc-3
220
LLPS-Cae-0649
WBGene00004896
Q9N4U5
smu-2
221
LLPS-Cae-0634
WBGene00016045
Q8MNV0
spas-1
222
LLPS-Cae-1764
WBGene00019006
O44735
spg-20
223
LLPS-Cae-0780
WBGene00005010
Q9XWP6
spr-5
224
LLPS-Cae-0500
WBGene00021312
Q9N537
szy-2
225
LLPS-Cae-1999
WBGene00012015
Q17761
T25B9.9
226
LLPS-Cae-1160
WBGene00006466
Q8WQE7
tag-115
227
LLPS-Cae-0719
WBGene00015230
O61821
tag-344
228
LLPS-Cae-1560
WBGene00004053
Q9TXQ1
tank-1
229
LLPS-Cae-1271
WBGene00006538
P41937
tbb-4
230
LLPS-Cae-1311
WBGene00018075
H2KZZ6
tbc-11
231
LLPS-Cae-1796
WBGene00044609
Q3V5J2
tbcc-1
232
LLPS-Cae-0592
WBGene00008887
Q19493
tbcd-1
233
LLPS-Cae-1434
WBGene00016352
Q18386
tbck-1
234
LLPS-Cae-1575
WBGene00010785
Q23670
top-2
235
LLPS-Cae-0947
WBGene00006599
P34722
tpa-1
236
LLPS-Cae-1280
WBGene00017686
Q09541
tpp-2
237
LLPS-Cae-0718
WBGene00015658
O76258
tsg-101
238
LLPS-Cae-1631
WBGene00006702
Q95XN7
ubc-3
239
LLPS-Cae-0778
WBGene00019163
Q8WTJ4
ubxn-6
240
LLPS-Cae-0297
WBGene00006793
Q9U334
unc-59
241
LLPS-Cae-0788
WBGene00006798
O16000
unc-64
242
LLPS-Cae-1306
WBGene00006808
E0AHC6
unc-76
243
LLPS-Cae-1025
WBGene00006816
Q20745
unc-84
244
LLPS-Cae-0397
WBGene00008441
G5EBW2
usp-50
245
LLPS-Cae-1731
WBGene00010565
Q21225
vacl-14
246
LLPS-Cae-0916
WBGene00020866
Q9GYK4
vps-24
247
LLPS-Cae-1695
WBGene00007047
O45797
wts-1
248
LLPS-Cae-1371
WBGene00002078
Q23089
xpo-1
249
LLPS-Cae-0412
WBGene00012476
Q9XW15
Y18D10A.3
250
LLPS-Cae-0822
WBGene00014170
Q09384
ZK945.8