Oryctolagus cuniculus      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orc-1256
ENSOCUG00000017400.2
G1TDM2
POP1
2
LLPS-Orc-1316
ENSOCUG00000015974.3
G1TAM1
POP4
3
LLPS-Orc-1761
ENSOCUG00000006896.3
G1SRX9
RPP30
4
LLPS-Orc-0053
ENSOCUG00000001861.3
G1SGA9
XRN1