Latimeria chalumnae      TAM body


※ TAM body introduction

    Specialized structures in S.cerevisiae referred to as TAM bodies (temporal asymmetric MRP bodies) are observed exclusively during mitosis. These structures contain Xrn1p but also RNase mitochondrial RNA processing (MRP), which is an essential and highly conserved RNP complex found in eukaryotes. RNase MRP is involved in ribosome biogenesis by processing ribosomal RNA transcripts to produce primers for mitochondrial DNA replication and it cleaves S.cerevisiae B-type cyclin (CLB2) mRNA. Colocalization of Xrn1p with RNase MRP to GW/P body-like structures suggests these ribonucleases regulate mitosis by degrading mRNAs encoding cell cycle regulators (1).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID:23224973


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lac-1103
ENSLACG00000012498.1
H3AX24
POP1
2
LLPS-Lac-2125
ENSLACG00000008581.2
H3AJB1
POP4
3
LLPS-Lac-3405
ENSLACG00000018188.1
H3BFM9
POP5
4
LLPS-Lac-1075
ENSLACG00000002534.1
H2ZZL5
RPP30
5
LLPS-Lac-0084
ENSLACG00000009020.1
H3AKR8
XRN1