Rattus norvegicus      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 10 genes.  Reviewed (2 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ran-0010
ENSRNOG00000052343.3
P63074
Eif4e
2
LLPS-Ran-0040
ENSRNOG00000007781.6
Q9ET50
Stau1
3
LLPS-Ran-1363
ENSRNOG00000000614.6
D3ZDJ9
Bicc1
4
LLPS-Ran-4021
ENSRNOG00000023661.6
Q792H5
Celf2
5
LLPS-Ran-0391
ENSRNOG00000020689.8
D4AD99
Cpeb3
6
LLPS-Ran-1168
ENSRNOG00000031387.4
Q4KLZ3
Dazap1
7
LLPS-Ran-0927
ENSRNOG00000007340.7
D3ZZJ7
Dcp1b
8
LLPS-Ran-1160
ENSRNOG00000045895.3
M0RBQ1
Dcp2
9
LLPS-Ran-3301
ENSRNOG00000017212.7
B0BMX8
Spsb1
10
LLPS-Ran-1048
ENSRNOG00000023786.6
P62961
Ybx1