Mus musculus      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 11 genes.  Reviewed (6 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mum-3168
ENSMUSG00000002107.18
Q9Z0H4
Celf2
2
LLPS-Mum-0571
ENSMUSG00000024472.9
Q9CYC6
Dcp2
3
LLPS-Mum-1951
ENSMUSG00000028156.12
P63073
Eif4e
4
LLPS-Mum-1345
ENSMUSG00000000568.15
Q60668
Hnrnpd
5
LLPS-Mum-1794
ENSMUSG00000025920.19
Q8CJ67
Stau2
6
LLPS-Mum-0488
ENSMUSG00000028639.14
P62960
Ybx1
7
LLPS-Mum-4830
ENSMUSG00000014329.14
Q99MQ1
Bicc1
8
LLPS-Mum-3270
ENSMUSG00000039652.16
Q7TN99
Cpeb3
9
LLPS-Mum-0131
ENSMUSG00000069565.12
Q9JII5
Dazap1
10
LLPS-Mum-3130
ENSMUSG00000041477.14
Q3U564
Dcp1b
11
LLPS-Mum-4467
ENSMUSG00000039911.13
Q9D5L7
Spsb1