Homo sapiens      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 12 genes.  Reviewed (10 or Unreviewed (2

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Hos-2397
ENSG00000122870.11
Q9H694
BICC1
2
LLPS-Hos-2698
ENSG00000048740.18
O95319
CELF2
3
LLPS-Hos-2549
ENSG00000107864.14
Q8NE35
CPEB3
4
LLPS-Hos-1950
ENSG00000071626.16
Q96EP5
DAZAP1
5
LLPS-Hos-0418
ENSG00000151065.13
Q8IZD4
DCP1B
6
LLPS-Hos-0522
ENSG00000172795.15
Q8IU60
DCP2
7
LLPS-Hos-0982
ENSG00000110367.12
P26196
DDX6
8
LLPS-Hos-2022
ENSG00000138668.18
Q14103
HNRNPD
9
LLPS-Hos-2653
ENSG00000124214.19
O95793
STAU1
10
LLPS-Hos-1533
ENSG00000060138.12
P16989
YBX3
11
LLPS-Hos-3995
ENSG00000175766.12
A6NMX2
EIF4E1B
12
LLPS-Hos-3502
ENSG00000171621.13
Q96BD6
SPSB1