Drosophila melanogaster      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 14 genes.  Reviewed (14 or Unreviewed (0

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Drm-0053
FBgn0000182
Q24009
BicC
2
LLPS-Drm-0131
FBgn0000114
Q8IP90
bru1
3
LLPS-Drm-2397
FBgn0000392
Q9VMA3
cup
4
LLPS-Drm-0170
FBgn0034921
Q9W1H5
DCP1
5
LLPS-Drm-0016
FBgn0036534
Q5U127
DCP2
6
LLPS-Drm-0088
FBgn0015218
P48598
eIF4E1
7
LLPS-Drm-2400
FBgn0000615
P28750
exu
8
LLPS-Drm-0237
FBgn0026238
A1Z6E0
gus
9
LLPS-Drm-0059
FBgn0004838
P48809
Hrb27C
10
LLPS-Drm-0108
FBgn0004419
P23128
me31B
11
LLPS-Drm-0165
FBgn0264307
Q9VSR3
orb2
12
LLPS-Drm-0113
FBgn0263396
Q08473
sqd
13
LLPS-Drm-0171
FBgn0003520
P25159
stau
14
LLPS-Drm-0134
FBgn0022959
Q95RE4
yps