Caenorhabditis elegans      Sponge body


※ Sponge body introduction

    Sponge bodies are 500-3,000 nm structures which are embedded in an electron dense matrix that is free of ribosomes. Btz, Tral, Cup, eIF4E, Me31B, Yps, Gus, Dcp1/2, Sqd, BicC, Hrb27C, Bru were identified in sponge bodies with Exu-GFP indicating that these structures have a role in post-transcriptional gene regulation (1). Since sponge bodies are typical proteinaceous membrane-less organelles, liquid–liquid phase separation is shown in the formation and disassembly of sponge bodies.

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973


There are 10 genes.  Reviewed (3 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cae-0129
WBGene00000479
Q95YF3
cgh-1
2
LLPS-Cae-0303
WBGene00021929
Q9N363
dcap-1
3
LLPS-Cae-0019
WBGene00003582
O62255
dcap-2
4
LLPS-Cae-1186
WBGene00000246
Q21593
bcc-1
5
LLPS-Cae-0552
WBGene00000472
O62213
cey-1
6
LLPS-Cae-1338
WBGene00000770
Q03571
cpb-1
7
LLPS-Cae-0651
WBGene00002061
O61955
ife-3
8
LLPS-Cae-2014
WBGene00021597
Q965N6
spsb-1
9
LLPS-Cae-1765
WBGene00022235
Q4W5P0
sqd-1
10
LLPS-Cae-0792
WBGene00018857
Q94239
stau-1