Ursus maritimus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Urm-0614
ENSUMAG00000012761.1
2
LLPS-Urm-1884
ENSUMAG00000020440.1
3
LLPS-Urm-1992
ENSUMAG00000002729.1
A0A384CSB7
AURKA
4
LLPS-Urm-1658
ENSUMAG00000004196.1
A0A384DCL5
AURKC
5
LLPS-Urm-3093
ENSUMAG00000017816.1
A0A384BYH4
CDC6
6
LLPS-Urm-3726
ENSUMAG00000020207.1
A0A384BKK9
CHAMP1
7
LLPS-Urm-1753
ENSUMAG00000019397.1
A0A384DDL8
CKAP2
8
LLPS-Urm-0367
ENSUMAG00000014345.1
A0A384CXN0
CKAP5
9
LLPS-Urm-0639
ENSUMAG00000024939.1
A0A384DNA6
CSRP2BP
10
LLPS-Urm-2914
ENSUMAG00000006169.1
A0A384CF14
DCTN3
11
LLPS-Urm-1662
ENSUMAG00000016056.1
A0A384CZZ0
DLGAP5
12
LLPS-Urm-0979
ENSUMAG00000003466.1
A0A384D0K0
DPYSL2
13
LLPS-Urm-2882
ENSUMAG00000025354.1
A0A384BL15
DYRK3
14
LLPS-Urm-2427
ENSUMAG00000009012.1
A0A384BU14
FES
15
LLPS-Urm-1104
ENSUMAG00000012736.1
A0A384D5Z5
GPSM2
16
LLPS-Urm-3065
ENSUMAG00000006573.1
A0A384DAC5
HAUS3
17
LLPS-Urm-1685
ENSUMAG00000017141.1
A0A384BZK8
HAUS6
18
LLPS-Urm-1450
ENSUMAG00000017153.1
A0A384C7H1
KATNAL1
19
LLPS-Urm-0794
ENSUMAG00000002681.1
A0A384CHX8
KIF11
20
LLPS-Urm-0838
ENSUMAG00000003710.1
A0A384BYM9
MAD2L1
21
LLPS-Urm-3955
ENSUMAG00000022879.1
A0A384CDM2
MAD2L2
22
LLPS-Urm-2735
ENSUMAG00000019164.1
A0A384DAZ2
MAPK6
23
LLPS-Urm-2363
ENSUMAG00000024172.1
A0A384D2Y6
MAPRE1
24
LLPS-Urm-2507
ENSUMAG00000023560.1
A0A384CRM1
MKNK1
25
LLPS-Urm-3310
ENSUMAG00000017064.1
A0A384DPG7
MSN
26
LLPS-Urm-2984
ENSUMAG00000022988.1
A0A384CDN2
MTOR
27
LLPS-Urm-2754
ENSUMAG00000020650.1
A0A384DQR3
MTUS1
28
LLPS-Urm-0752
ENSUMAG00000016001.1
A0A384CJ12
NCOA4
29
LLPS-Urm-0853
ENSUMAG00000005301.1
A0A384CJX1
NDE1
30
LLPS-Urm-0529
ENSUMAG00000016128.1
A0A384BHU6
PARD3
31
LLPS-Urm-0601
ENSUMAG00000017815.1
A0A384CA26
RANBP9
32
LLPS-Urm-3312
ENSUMAG00000007347.1
A0A384BRM7
RBPMS
33
LLPS-Urm-2071
ENSUMAG00000010525.1
A0A384C255
SEPT2
34
LLPS-Urm-2063
ENSUMAG00000023728.1
A0A384BKK3
SMC3
35
LLPS-Urm-1296
ENSUMAG00000005940.1
A0A384CPY2
SUN1
36
LLPS-Urm-3480
ENSUMAG00000014464.1
A0A384D9Q9
SUN2
37
LLPS-Urm-0954
ENSUMAG00000018861.1
A0A384CNV3
TADA3
38
LLPS-Urm-0776
ENSUMAG00000020898.1
A0A384CNA3
TPR
39
LLPS-Urm-0773
ENSUMAG00000015371.1
A0A384CGK2
ZNF207