Takifugu rubripes      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 35 genes.  Reviewed (0 or Unreviewed (35

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tar-1140
ENSTRUG00000001921.2
H2RWA8
2
LLPS-Tar-3604
ENSTRUG00000004493.2
H2SE40
3
LLPS-Tar-0817
ENSTRUG00000005830.2
H2SP68
cdc6
4
LLPS-Tar-0269
ENSTRUG00000015453.2
H2URF6
ckap5
5
LLPS-Tar-2047
ENSTRUG00000002197.2
H2RY27
cltb
6
LLPS-Tar-1812
ENSTRUG00000000343.2
H2RKX5
dctn3
7
LLPS-Tar-1153
ENSTRUG00000016800.2
H2V1F4
dlgap5
8
LLPS-Tar-2183
ENSTRUG00000018073.2
H2VAN4
fes
9
LLPS-Tar-4017
ENSTRUG00000014852.2
H2ULX6
gpsm2
10
LLPS-Tar-2704
ENSTRUG00000003100.2
H2S4C1
haus6
11
LLPS-Tar-2837
ENSTRUG00000012026.2
H2U0H3
kat14
12
LLPS-Tar-3532
ENSTRUG00000006850.2
H2SWN0
KATNA1
13
LLPS-Tar-0794
ENSTRUG00000012228.2
H2U1Z5
kif11
14
LLPS-Tar-0578
ENSTRUG00000012490.2
H2U3X9
LOC101067325
15
LLPS-Tar-3176
ENSTRUG00000015416.2
A0A3B5KL40
LOC101072012
16
LLPS-Tar-1692
ENSTRUG00000000788.2
H2RP35
LOC101072077
17
LLPS-Tar-2072
ENSTRUG00000023953.1
A0A3B5KDZ7
LOC101077793
18
LLPS-Tar-1468
ENSTRUG00000002983.2
H2S3K0
LOC101079435
19
LLPS-Tar-0546
ENSTRUG00000023674.1
A0A3B5K988
mad2l1
20
LLPS-Tar-3052
ENSTRUG00000000942.2
A0A3B5K6J6
mad2l2
21
LLPS-Tar-2400
ENSTRUG00000017013.2
A0A3B5KNU8
mapk6
22
LLPS-Tar-0500
ENSTRUG00000022779.1
A0A3B5KI06
mapre1
23
LLPS-Tar-3571
ENSTRUG00000005698.2
H2SN24
marveld1
24
LLPS-Tar-0415
ENSTRUG00000017658.2
H2V7R3
mknk1
25
LLPS-Tar-2814
ENSTRUG00000003924.2
H2SA35
ncoa4
26
LLPS-Tar-2439
ENSTRUG00000014588.2
H2UK08
prc1
27
LLPS-Tar-2134
ENSTRUG00000005581.2
A0A3B5KD73
ranbp10
28
LLPS-Tar-0071
ENSTRUG00000000041.2
H2RIY6
RBPMS
29
LLPS-Tar-1582
ENSTRUG00000021827.1
A0A3B5JYG0
sept2
30
LLPS-Tar-1225
ENSTRUG00000006942.2
H2SXA8
smc3
31
LLPS-Tar-0361
ENSTRUG00000015866.2
H2UUE1
sun1
32
LLPS-Tar-0714
ENSTRUG00000010855.2
H2TRW9
tada3
33
LLPS-Tar-2319
ENSTRUG00000010078.2
H2TL02
tmem201
34
LLPS-Tar-1672
ENSTRUG00000009240.2
H2TEZ2
tpx2
35
LLPS-Tar-3313
ENSTRUG00000021140.1
A0A3B5JYG3
znf207