Taeniopygia guttata      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 33 genes.  Reviewed (0 or Unreviewed (33

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tag-0588
ENSTGUG00000003712.1
H0YZU4
2
LLPS-Tag-2554
ENSTGUG00000008358.1
H0ZDG9
3
LLPS-Tag-3041
ENSTGUG00000002293.1
H0YVN9
CDC6
4
LLPS-Tag-2432
ENSTGUG00000009515.1
H0ZGV0
CHAMP1
5
LLPS-Tag-1168
ENSTGUG00000012041.1
H0ZP76
CKAP2
6
LLPS-Tag-0141
ENSTGUG00000000535.1
H0YQJ4
CLTB
7
LLPS-Tag-0819
ENSTGUG00000001729.1
B5G3H3
DCTN3
8
LLPS-Tag-1383
ENSTGUG00000013075.1
H0ZS68
DLGAP5
9
LLPS-Tag-0297
ENSTGUG00000004168.1
H0Z199
DPYSL2
10
LLPS-Tag-3383
ENSTGUG00000001091.1
H0YS59
DYRK3
11
LLPS-Tag-1646
ENSTGUG00000010113.1
H0ZIM7
FES
12
LLPS-Tag-3056
ENSTGUG00000004521.1
H0Z270
GPSM2
13
LLPS-Tag-0336
ENSTGUG00000010536.1
H0ZJU6
HAUS3
14
LLPS-Tag-2230
ENSTGUG00000005899.1
H0Z668
KAT14
15
LLPS-Tag-1231
ENSTGUG00000011690.1
H0ZN79
KATNAL1
16
LLPS-Tag-0118
ENSTGUG00000008927.1
H0ZF48
KIF11
17
LLPS-Tag-1119
ENSTGUG00000001917.1
H0YUK6
MAD2L1
18
LLPS-Tag-0614
ENSTGUG00000002334.1
H0YVT5
MAD2L2
19
LLPS-Tag-1458
ENSTGUG00000010816.1
H0ZKN3
MAPRE2
20
LLPS-Tag-3604
ENSTGUG00000009603.1
H0ZH29
MARVELD1
21
LLPS-Tag-3593
ENSTGUG00000002826.1
H0YX94
MSN
22
LLPS-Tag-3202
ENSTGUG00000002263.1
H0YVP9
MTOR
23
LLPS-Tag-3373
ENSTGUG00000007145.1
H0Z9X1
MTUS1
24
LLPS-Tag-2247
ENSTGUG00000005818.1
H0Z603
NCOA4
25
LLPS-Tag-0520
ENSTGUG00000000932.1
H0YRQ8
PARD3
26
LLPS-Tag-0167
ENSTGUG00000005262.1
H0Z4E2
RANBP10
27
LLPS-Tag-1246
ENSTGUG00000001776.1
H0YU64
RBPMS
28
LLPS-Tag-0400
ENSTGUG00000006160.1
H0Z6Z9
SEPT2
29
LLPS-Tag-0199
ENSTGUG00000010610.1
H0ZK70
SMC3
30
LLPS-Tag-2895
ENSTGUG00000010300.1
H0ZJ94
SUN2
31
LLPS-Tag-3027
ENSTGUG00000008689.1
H0ZEF0
TADA3
32
LLPS-Tag-0804
ENSTGUG00000003515.1
H0YZH1
TPR
33
LLPS-Tag-1560
ENSTGUG00000004789.1
H0Z306
ZNF207