Oryzias latipes      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 32 genes.  Reviewed (0 or Unreviewed (32

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orl-3792
ENSORLG00000000484.2
H2L4B9
2
LLPS-Orl-3216
ENSORLG00000000130.2
H2L356
cdc6
3
LLPS-Orl-1910
ENSORLG00000014504.2
H2MHR3
ckap5
4
LLPS-Orl-3414
ENSORLG00000026832.1
A0A3B3IBX0
cltb
5
LLPS-Orl-1052
ENSORLG00000003444.2
H2LEA9
dlgap5
6
LLPS-Orl-1412
ENSORLG00000015659.2
H2MLM7
gpsm2
7
LLPS-Orl-3475
ENSORLG00000005097.3
H2LK79
haus6
8
LLPS-Orl-2487
ENSORLG00000020896.2
H2N323
kat14
9
LLPS-Orl-1923
ENSORLG00000002076.2
H2L9P6
kif11
10
LLPS-Orl-0520
ENSORLG00000023847.1
A0A3B3ICP8
LOC101155946
11
LLPS-Orl-1979
ENSORLG00000009173.2
A0A3B3HTP4
LOC101156778
12
LLPS-Orl-1444
ENSORLG00000011618.2
H2M7V7
LOC101163120
13
LLPS-Orl-1707
ENSORLG00000005653.2
H2LM39
LOC101163655
14
LLPS-Orl-2085
ENSORLG00000023253.1
A0A3B3IKL1
LOC101164183
15
LLPS-Orl-1878
ENSORLG00000004135.2
H2LGS3
LOC101164593
16
LLPS-Orl-1054
ENSORLG00000018633.2
A0A3B3IMS3
LOC101169996
17
LLPS-Orl-0644
ENSORLG00000002669.2
H2LBP8
LOC101173310
18
LLPS-Orl-0200
ENSORLG00000020784.2
H2N2Q1
mad2l1
19
LLPS-Orl-3652
ENSORLG00000003082.2
H2LD47
mapk6
20
LLPS-Orl-2650
ENSORLG00000020223.2
H2N103
mapre1
21
LLPS-Orl-3745
ENSORLG00000027726.1
A0A3B3IJI2
marveld1
22
LLPS-Orl-0601
ENSORLG00000016569.2
H2MPT3
mknk1
23
LLPS-Orl-1815
ENSORLG00000003269.2
A0A3B3IG10
ncoa4
24
LLPS-Orl-2931
ENSORLG00000002125.2
H2L9V0
pard3
25
LLPS-Orl-2093
ENSORLG00000006296.2
A0A3B3I1E9
ranbp9
26
LLPS-Orl-0478
ENSORLG00000015257.2
A0A3B3HL13
smc3
27
LLPS-Orl-2326
ENSORLG00000013394.2
H2MDZ4
tada3
28
LLPS-Orl-2895
ENSORLG00000005435.2
H2LLD1
tmem201
29
LLPS-Orl-1523
ENSORLG00000009423.2
H2M097
tpr
30
LLPS-Orl-3014
ENSORLG00000018848.2
H2MX85
tpx2
31
LLPS-Orl-1826
ENSORLG00000027351.1
A0A3B3HGU4
zbtb4
32
LLPS-Orl-2299
ENSORLG00000023077.1
A0A3B3H5P8
ZNF207 (1 of many)