Oryctolagus cuniculus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orc-1710
ENSOCUG00000023933.1
G1TYC4
2
LLPS-Orc-1617
ENSOCUG00000017898.3
G1TEP5
AURKA
3
LLPS-Orc-0172
ENSOCUG00000011337.2
G1T141
AURKC
4
LLPS-Orc-4087
ENSOCUG00000004898.3
G1SMR6
CDC6
5
LLPS-Orc-1257
ENSOCUG00000001588.2
G1SFQ2
CHAMP1
6
LLPS-Orc-0914
ENSOCUG00000016200.2
G1TB71
CKAP5
7
LLPS-Orc-1614
ENSOCUG00000014826.3
G1T868
CLTB
8
LLPS-Orc-0938
ENSOCUG00000000358.1
G1SD49
DCTN3
9
LLPS-Orc-0005
ENSOCUG00000002926.3
G1SIN2
DLGAP5
10
LLPS-Orc-1905
ENSOCUG00000016002.3
G1U974
DPYSL2
11
LLPS-Orc-1936
ENSOCUG00000007421.3
G1ST08
DYRK3
12
LLPS-Orc-3040
ENSOCUG00000003627.3
G1SK35
GPSM2
13
LLPS-Orc-1234
ENSOCUG00000021362.2
G1U4N2
HAUS3
14
LLPS-Orc-1278
ENSOCUG00000003507.3
G1SJV4
HAUS6
15
LLPS-Orc-0002
ENSOCUG00000015365.3
G1T9A2
KAT14
16
LLPS-Orc-3009
ENSOCUG00000003387.3
B7NZ88
KATNAL1
17
LLPS-Orc-1236
ENSOCUG00000016706.3
G1TC72
KIF11
18
LLPS-Orc-1860
ENSOCUG00000022541.1
G1U8Z6
LOC100343344
19
LLPS-Orc-0008
ENSOCUG00000008243.3
G1SUS1
MAD2L1
20
LLPS-Orc-2400
ENSOCUG00000003176.2
G1SJ65
MAD2L2
21
LLPS-Orc-2487
ENSOCUG00000024265.1
G1U949
MAPRE1
22
LLPS-Orc-4028
ENSOCUG00000025329.1
G1TK22
MARVELD1
23
LLPS-Orc-0265
ENSOCUG00000003495.3
G1U689
MKNK1
24
LLPS-Orc-4119
ENSOCUG00000000149.2
G1SCP8
MSN
25
LLPS-Orc-0580
ENSOCUG00000013053.3
G1T4N5
MTOR
26
LLPS-Orc-1288
ENSOCUG00000005218.3
G1SNG1
MTUS1
27
LLPS-Orc-2800
ENSOCUG00000000455.3
G1SDC0
PARD3
28
LLPS-Orc-1650
ENSOCUG00000006301.3
G1TU03
RANBP10
29
LLPS-Orc-0486
ENSOCUG00000008572.3
G1SVF1
RBPMS
30
LLPS-Orc-0953
ENSOCUG00000015500.3
G1U0Q7
SEPT2
31
LLPS-Orc-0585
ENSOCUG00000011142.3
G1T0Q6
SMC3
32
LLPS-Orc-4195
ENSOCUG00000010709.3
G1SZU7
SPAG4
33
LLPS-Orc-3728
ENSOCUG00000023106.2
G1TQE5
SUN3
34
LLPS-Orc-0843
ENSOCUG00000027231.1
G1TND6
TADA3
35
LLPS-Orc-2963
ENSOCUG00000004170.3
G1SL81
TMEM201
36
LLPS-Orc-1704
ENSOCUG00000012261.3
G1T2Y5
TPR
37
LLPS-Orc-0222
ENSOCUG00000007437.3
G1ST22
ZBTB4
38
LLPS-Orc-0716
ENSOCUG00000008195.3
G1SUP4
ZNF207